Closed

Promoting implementation of research results into policy and practice

HORIZON JU Research and Innovation Actions

Basic Information

Identifier
HORIZON-JU-GH-EDCTP3-2022-CALL1-01-01
Programme
Research and Innovation actions supporting the global health EDCTP3 Joint Undertaking
Programme Period
2021 - 2027
Status
Closed (31094503)
Opening Date
May 10, 2022
Deadline
August 29, 2022
Deadline Model
single-stage
Budget
€38,030,000
Min Grant Amount
€4,000,000
Max Grant Amount
€4,000,000
Expected Number of Grants
9
Keywords
HORIZON-JU-GH-EDCTP3-2022-CALL1-01-01HORIZON-JU-GH-EDCTP3-2022-01Clinical trialsGlobal healthHealth inequalitiesHealth policiesHealth promotionHealth sciencesInfectious diseasesPrevention and treatment of infection by pathogens (e.g. vaccination, antibiotics, fungicide)

Description

Expected Outcome:

This topic aims at supporting activities that contribute to one or several of the expected impacts for this call. To that end, proposals under this topic should aim for delivering results that are contributing to the following expected outcomes:

  • Uptake of research results into clinical practice so that people in sub-Saharan Africa, particularly vulnerable populations, can have access to safe health technologies[1] of proven efficacy for poverty-related diseases, including emerging and re-emerging infectious diseases and antimicrobial resistant infections;
  • Operational and evaluation tools for successfully translating research results into clinical practice are validated and health systems in sub-Saharan Africa are improved;
  • Widespread adoption of research results into national and international policy guidelines.
Scope:

Failure to translate research findings into policy and practice prevents research from achieving maximum public health benefit. Despite substantial investment in clinical research in poverty-related diseases, including emerging and re-emerging infectious diseases and antimicrobial-resistant infections, exploitation and use of results beyond research groups to date remains limited. The barriers to an efficient uptake of research results include limited interaction between researchers, policymakers, patients’ community and other stakeholders, lack of experience in exploiting research results beyond academia, limited health systems capacity, affordability issues, and structural and cultural differences between the realms of research, programme planning and policymaking.

Proposals should address the following activities:

  • Carry out registration and/or post-registration studies of health technologies (such as pragmatic effectiveness studies) that address diseases within the scope of GH EDCTP3 to demonstrate the clinical effectiveness in relevant patient populations;
  • Demonstrate the cost effectiveness of the health technologies being investigated in relevant communities;
  • Identify barriers to uptake of the health technologies being investigated and address them in the studies to be carried out;
  • Develop methods and evaluation tools that can ensure translating clinical research results into healthcare policy and practice. These methods should be broadly applicable to improve patients quality of life beyond the specific health technology being investigated;
  • Early involvement and regular interaction with policy and decision makers as well as end-users to have the health technology adopted by health systems.

Applicants need to concisely describe any prior research findings and explain how the proposal builds on these results. Building on results from projects supported under previous EDCTP programmes is encouraged.

Proposals should present a sound assessment of the feasibility of the proposed work, especially as regards the planned clinical investigations. Realistic plans for recruiting trial subjects should be presented and corroborated by demonstrated success from previous studies. The proposals should justify the choice of populations to be enrolled into the trials and explain how they relate to the larger population. The full range of relevant determining characteristics (sex, gender, age, socio-economic status, etc.) needs also to be considered.

Proposals should describe how stakeholder views of the proposal’s relevance and the study design have been incorporated in the co-creation process of planning the research proposal. Proposals should indicate explicit plans for good participatory practices for engaging stakeholders at every step of the research life-cycle.

Proposals should provide details on the methodology for linking clinical research aspects with the translation into healthcare practice and policy.

Applicants are welcome to draw on any relevant lessons from knowledge translation in response to the COVID-19 pandemic.

It is essential that proposals bring together clinical researchers with experience in implementation research, health policy experts and end users.

[1] The definition of health technology is the application of organized knowledge and skills in the form of medicines, medical devices, vaccines, procedures and systems developed to solve a health problem and improve quality of life.

Eligibility & Conditions

General conditions

General conditions

1. Admissibility conditions: described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes

 

 

Proposal page limits and layout: described in Part B of the Application Form available in the Submission System

 

 

2. Eligible countries: 

According to Article 110 of the Council Regulation (EU) 2021/2085, funding from the  Global Health EDCTP3 Joint Undertaking is restricted to legal entities established in Member States or associated countries or in the constituent states of the EDCTP Association.

Constituent states of the EDCTP Association that are not Member States or associated countries are: Burkina Faso, Cameroon, Congo, Côte d’Ivoire, Ethiopia, Gabon, The Gambia, Ghana, Kenya, Mali, Mozambique, Niger, Nigeria, Senegal, South Africa, Tanzania, Uganda, United Kingdom, Zambia.

A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.

 

3. Other eligibility conditions: described in Annex B of the Work Programme General Annexes, except for the specific conditions for GH EDCTP3 funding as regards Entities eligible for funding and Consortium composition.

Entities eligible to participate

Given the illegal invasion of Ukraine by Russia and the involvement of Belarus, there is currently no appropriate context allowing the implementation of the actions foreseen in this programme with legal entities established in Russia, Belarus, or in non-government controlled territories of Ukraine. Therefore, such legal entities are not eligible to participate in any capacity. This criterion also applies in cases where the action involves financial support given by grant beneficiaries to third parties established in Russia, Belarus or in non-government controlled territories of Ukraine (in accordance with Article 204 of the Financial Regulation No 2018/1046).

Entities eligible for funding

To be eligible for funding, applicants must be eligible to participate and established in one of the eligible countries, i.e.

-          The Member States of the European Union, including their outermost regions;

-          The Oversees Countries and Territories (OCTs) linked to Member States[1]

-          Eligible non-EU countries:

o   Countries associated to Horizon Europe[2]

o   Countries that are members of the EDCTP Association[3]

Legal entities which are established in countries not listed above will be eligible for funding if provided for in the specific call conditions, or if the participation is considered essential for implementing the action by the granting authority.



[1] Entities from Oversees Countries and Territories (OCT) are eligible for funding under the same conditions as entities from the Member State to which the OCT in question is linked. See the Horizon Europe Programme Guide for a complete list of OCTs.

[3] See the EDCTP website

 

 

4. Financial and operational capacity and exclusion: described in Annex C of the Work Programme General Annexes

 

  • Award criteria  are described in Annex D of the Work Programme General Annexes.
  • Scoring and thresholds are as follows:

    Evaluation scores will be awarded for the criteria, and not for the different aspects listed in the table. For full applications, each criterion will be scored out of 5. The threshold for individual criteria 1 (Excellence) and 2 (Impact) will be 4 and for criteria 3 (Quality and efficiency of the implementation) will be 3. The overall threshold, applying to the sum of the three individual scores, will be 12.

    Proposals that pass the individual threshold AND the overall threshold will be considered for funding, within the limits of the available call budget. Other proposals will be rejected.

  • Submission and evaluation processes are described in Annex F of the Work Programme General Annexes and the Online Manual

  • Indicative timeline for evaluation and grant agreement: described in Annex F of the Work Programme General Annexes

Implementing the provision on affordable access as defined in Article 114 of the 2021/2085 Council Regulation establishing the Joint Undertakings under Horizon Europe[[Council Regulation (EU) 2021/2085 of 19 November 2021 establishing the Joint Undertakings under Horizon Europe and repealing Regulations (EC) No 219/2007, (EU) No 557/2014, (EU) No 558/2014, (EU) No 559/2014, (EU) No 560/2014, (EU) No 561/2014 and (EU) No 642/2014; OJ L 427, 30.11.2021, p. 17]], grants award under this topic will have to submit the following deliverables:

1. Stewardship plan

Beneficiaries must prepare stewardship plans outlining how to achieve the optimal use of an intervention, including, for example, how to avoid irrational use, overuse or abuse of health technologies (e.g. antimicrobials). A draft plan must be submitted after half the duration of the project has elapsed and a final plan must be submitted with the final report.

2. Global access plan

With the final report, beneficiaries must submit an appropriate and proportionate global access plan that covers registration targets, plans to meet demand, flexible approaches to IP and other strategies that reflect ability to pay and ensure that economic barriers to access are low.

Also in line with Article 114 of the 2021/2085 Council Regulation, participants will be subject to the following additional exploitation obligations:

  1. Participants must – up to four years after the end of the action (see Data Sheet, Point 1) – use their best efforts to ensure that resulting health technologies and services will be broadly available and accessible, as soon as possible and at fair and reasonable conditions. In this respect, if, despite a participants’ best efforts, the results are not exploited within one year after the end of the action, participants must (unless otherwise agreed in writing with the granting authority) use the Horizon Results Platform to find interested parties to exploit the results.
  2. In case the participants cannot fulfil the preceding obligation, the participants must (if requested by the granting authority) grant non-exclusive licences - under fair and reasonable conditions - to their results to legal entities that commit to rapidly and broadly exploiting the resulting health technologies and services and ensure that they are broadly available and accessible, as soon as possible and at fair and reasonable conditions.

In case of transfer of the ownership or licensing of results, participants must pass on such additional exploitation obligations to the legal entities exploiting the results.

For up to four years after the action (see Data Sheet, Point 1), the funding body must be informed every year about the status of the development of the product or any other exploitation of the results through an annual report that is due on each anniversary of the end of the grant agreement.

 

6. Legal and financial set-up of the grants: described in Annex G of the Work Programme General Annexes

 

Specific conditions

7. Specific conditions: described in the specific topic of the Work Programme

Support & Resources

Online Manual is your guide on the procedures from proposal submission to managing your grant.

Horizon Europe Programme Guide contains the detailed guidance to the structure, budget and political priorities of Horizon Europe.

Funding & Tenders Portal FAQ – find the answers to most frequently asked questions on submission of proposals, evaluation and grant management.

Research Enquiry Service – ask questions about any aspect of European research in general and the EU Research Framework Programmes in particular.

National Contact Points (NCPs) – get guidance, practical information and assistance on participation in Horizon Europe. There are also NCPs in many non-EU and non-associated countries (‘third-countries’).

Enterprise Europe Network – contact your EEN national contact for advice to businesses with special focus on SMEs. The support includes guidance on the EU research funding.

IT Helpdesk – contact the Funding & Tenders Portal IT helpdesk for questions such as forgotten passwords, access rights and roles, technical aspects of submission of proposals, etc.

European IPR Helpdesk assists you on intellectual property issues.

CEN-CENELEC Research Helpdesk and ETSI Research Helpdesk –  the European Standards Organisations advise you how to tackle standardisation in your project proposal.  

The European Charter for Researchers and the Code of Conduct for their recruitment– consult the general principles and requirements specifying the roles, responsibilities and entitlements of researchers, employers and funders of researchers.

Partner Search Services help you find a partner organisation for your proposal.

 

Latest Updates

Last Changed: December 22, 2022

Information for the Funding Portal

Number proposals submitted: 92

Number Ineligible proposals: 11

Number proposals evaluated: 81

              - Number of Below threshold: 36

              - Number of Above threshold: 45

                               - Number of Main list: 26

                               - Number of Reserve list: 4

                               - Number rejected due to budgetary ressources: 15

 

Number of proposal upgraded from Reserve list to Main list: 1

Last Changed: October 7, 2022

Call HORIZON-JU-GH-EDCTP3-2022-01 closed on 30 August 2022. A total of 92 proposals were submitted. The breakdown per topic is:

·       HORIZON-JU-GH-EDCTP3-2022-CALL1-01-01: 40 proposals 

·       HORIZON-JU-GH-EDCTP3-2022-CALL1-01-02: 14 proposals

·       HORIZON-JU-GH-EDCTP3-2022-CALL1-01-03: 20 proposals

·       HORIZON-JU-GH-EDCTP3-2022-CALL1-01-04:  2 proposals

·       HORIZON-JU-GH-EDCTP3-2022-CALL1-01-05: 16 proposals

Evaluation results are expected to be communicated on Friday 21 November 2022 at the earliest.

Last Changed: May 17, 2022
The submission session is now available for: HORIZON-JU-GH-EDCTP3-2022-CALL1-01-01(HORIZON-JU-RIA), HORIZON-JU-GH-EDCTP3-2022-CALL1-01-04(HORIZON-JU-CSA), HORIZON-JU-GH-EDCTP3-2022-CALL1-01-03(HORIZON-JU-RIA), HORIZON-JU-GH-EDCTP3-2022-CALL1-01-02(HORIZON-JU-RIA), HORIZON-JU-GH-EDCTP3-2022-CALL1-01-05(HORIZON-JU-CSA)
Promoting implementation of research results into policy and practice | Grantalist