Open

Leveraging R&i Knowledge On Microbiome

HORIZON Coordination and Support Actions

Basic Information

Identifier
HORIZON-CL6-2026-02-FARM2FORK-12
Programme
Call 02 - single stage (2026)
Programme Period
2021 - 2027
Status
Open (31094502)
Opening Date
January 14, 2026
Deadline
April 14, 2026
Deadline Model
single-stage
Budget
€11,800,000
Min Grant Amount
€5,000,000
Max Grant Amount
€6,000,000
Expected Number of Grants
2
Keywords
HORIZON-CL6-2026-02-FARM2FORK-12HORIZON-CL6-2026-02AgricultureAtmospheric scienceBiological sciencesEarth and related environmental sciencesEcologyFood technologyHealth and FoodHealth sciencesNatureSoil science

Description

Expected Outcome:

Project results are expected to contribute to all the following expected outcomes:

  • provides a microbiome one-stop-shop containing resources and knowledge (information on microbiome R&I landscape, databases, best practices, risk assessments and food safety, aspects related to the environment and biodiversity, policy briefs…) for stakeholders involved in microbiome R&I (researchers, policymakers and regulators);
  • guidance for policymakers focusing on the integrated link between microbiome and its interconnection with human health, climate, environment, agriculture and food systems (emphasising the One Health perspective);
  • enhanced integration and coordination between member states and associated countries on microbiome research and innovation within a One Health context, encompassing all kinds of microbiomes.
Scope:

Microbiome research, adopting a holistic approach through a One Health perspective, has gained traction recently but research remains fragmented and there is a need for a coordination body that monitors research in this sector and steer research efforts in a strategical direction. Nevertheless, regulatory requirements remain one of the biggest challenges translating microbiome research to innovative solutions and such body would reinsure continuity of regulatory harmonisation efforts, conducted by previous and existing initiatives.

The topic is relevant to the EU policies related to the Commission communication on: Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU, the EU life science strategy, the EU biodiversity strategy for 2030, the zero pollution action plan, the EU strategy on research and technology infrastructure, the R&I food 2030 framework, and the digital transition policies (e.g., AI Act, etc).

Proposals should address all the following activities:

  • establishment of a hub acting as a resource centre and a monitoring body of the microbiome R&I and regulatory landscape; fostering and strengthening synergies between existing coordination efforts and national initiatives in alignment with EU microbiome initiatives;
  • mapping of all ongoing and past EU-based microbiome projects, EU research and technology infrastructures, and EU initiatives (public and private); identify overlaps, synergies, and gaps across all microbiome domains notably to inform future funding and policy directions;
  • collaborating with relevant ongoing initiatives (e.g. the World Microbiome Partnership), EU-funded projects (e.g. HORIZON-CL6-2026-02-FARM2FORK-11), and build on outcomes of legacy EU microbiome projects, among others, to ensure coordinated action, avoid duplication of efforts, build on existing achievements, and foster financial synergies by identifying microbiome R&I funding gaps;
  • monitoring and assessing the microbiome R&I impact on the population, the environment, biodiversity, the EU economy and competitiveness through specific indicators targeting EU and national policies priorities with an emphasis on One Health principles and across all microbiome types.

Destination & Scope

This destination will support the EU Commission priority ‘Sustaining our quality of life: food security, water and nature’.

R&I will provide new knowledge and innovation in support of the EU Vision for Agriculture and Food, built on the recommendations of the Strategic Dialogue on Agriculture, to ensure the long-term competitiveness and sustainability of our farming, fisheries, aquaculture and food sector within the boundaries of our planet. The implementation of the Green Deal actions will continue to guide R&I in this destination to foster sustainable food systems, addressing potential trade-offs between economic competitiveness and environmental sustainability.

The R&I activities under this Destination will contribute to the ambitious objectives of the current CAP concerning the competitiveness and sustainability of feed, food and non-food production as well as additional future CAP policy priorities. More specifically, actions will contribute to the specific objectives of the CAP; EU action plan for the development of organic production; food safety regulations; sustainable use of pesticides requirements under the plant protection products framework; action plan against antimicrobial resistance; animal health and welfare legislations; legislative and non-legislative initiatives to enhance cooperation of primary producers and improve their competitiveness and position in the food chain; protein strategy; contingency plan for ensuring food supply and food security and communications on food security and fertilizers, the Nature Restoration Regulation, the Zero Pollution Action Plan.

R&I will also support the announced Vision for the Fisheries Sector with a 2040 perspective and the European Ocean Pact, a framework of coherence across all policies linked to the ocean. R&I will also be relevant to the outcomes of the evaluation of the common fisheries policy (CFP) and will support its placement under this Pact, as fisheries and aquaculture are affected by other ocean related policies.

An important driving force of food systems transformation should be the integration of sectors, actors (including citizens and consumers) and policies. This will involve a better understanding of the multiple interactions between the components of current food systems, to foster solutions that maximise co-benefits with respect to the priorities of Food 2030[1].

The EU Communication on Boosting Biotechnology and Biomanufacturing in the[2] EU provides an overview of the application of biotechnologies in several sectors including food and feed. R&I activities in this destination will also contribute to achieving the objectives of the Strategy for European Life Sciences, the EU Biotech Act, and the new EU bioeconomy strategy.

The Destination supports unlocking the unique assets for research and innovation of the EU outermost regions, in line with the EU strategy for outermost regions[3].

Expected impact: Proposals for topics under this destination should set out credible paths to “ensuring healthy food and nutrition security by making agriculture, fisheries, aquaculture and food systems sustainable, resilient, inclusive and within planetary boundaries”. More specifically, proposed topics should contribute to one or more of the following expected impacts:

  • agriculture and food systems contribute to ensuring a secure, safe, sustainable, nutritious, and affordable supply of healthy food in Europe and beyond by fostering its long-term competitiveness, resilience, scalability and sustainability within the boundaries of our planet with the One Health approach;
  • farmers are empowered to ensure the competitiveness, resilience and sustainability of the farming sector, through increasing knowledge, tools, innovative solutions, and advice that allow efficient productivity, working for and with nature, preserving and restoring biodiversity within agricultural ecosystems and helping to decarbonise the EU economy;
  • sustainable fisheries and aquaculture (in marine, brackish and freshwater) contribute to fair, healthy, resilient and environment-friendly food systems in healthy aquatic ecosystems with thriving diversity of species and habitats providing ecosystem and climate services and triggering growth and jobs’ creation in coastal and rural areas;
  • tools are provided so that citizens and communities are empowered to make the sustainable food choices and move towards safe, healthy, nutritious, accessible, affordable and sustainable diets. Insights and advances in life science and digital & data technologies are valorised to deploy solutions in practice across the EU;
  • food businesses, including food processing industries and SMEs, are supported to increase their resilience and competitiveness, while ensuring resource efficiency and sustainability, and human, animal and ecosystem health is preserved.

[1] The four priorities of Food2030 are: 1) nutrition and health; 2) climate and environmental sustainability; 3) circularity and resource efficiency; and 4) innovation and empowering communities.

[2] https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:52024DC0137.

[3] COM(2022) Putting people first, securing sustainable and inclusive growth, unlocking the potential of the EU’s outermost regions.

Eligibility & Conditions

General conditions

1. Admissibility Conditions: Proposal page limit and layout

described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.

Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.

2. Eligible Countries

described in Annex B of the Work Programme General Annexes.

A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.

3. Other Eligible Conditions

described in Annex B of the Work Programme General Annexes.

4. Financial and operational capacity and exclusion

described in Annex C of the Work Programme General Annexes.

5a. Evaluation and award: Award criteria, scoring and thresholds

are described in Annex D of the Work Programme General Annexes.

5b. Evaluation and award: Submission and evaluation processes

are described in Annex F of the Work Programme General Annexes and the Online Manual.

5c. Evaluation and award: Indicative timeline for evaluation and grant agreement

described in Annex F of the Work Programme General Annexes.

6. Legal and financial set-up of the grants

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf]].

described in Annex G of the Work Programme General Annexes.

Specific conditions

described in the [specific topic of the Work Programme]

Frequently Asked Questions About Leveraging R&i Knowledge On Microbiome

Call 02 - single stage (2026) (2021 - 2027).
Per-award range: €5,000,000–€6,000,000. Total programme budget: €11,800,000. Expected awards: 2.
Deadline: April 14, 2026. Deadline model: single-stage.
Eligible organisation types (inferred): SMEs, Research organisations.
Admissibility Conditions: Proposal page limit and layout described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes. Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.
Legal and financial set-up of the grants Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf ]].
You can contact the organisers at [email protected].

Support & Resources

Online Manual is your guide on the procedures from proposal submission to managing your grant.

Horizon Europe Programme Guide contains the detailed guidance to the structure, budget and political priorities of Horizon Europe.

Funding & Tenders Portal FAQ – find the answers to most frequently asked questions on submission of proposals, evaluation and grant management.

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IT Helpdesk – contact the Funding & Tenders Portal IT helpdesk for questions such as forgotten passwords, access rights and roles, technical aspects of submission of proposals, etc.

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The European Charter for Researchers and the Code of Conduct for their recruitment – consult the general principles and requirements specifying the roles, responsibilities and entitlements of researchers, employers and funders of researchers.

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Latest Updates

Last Changed: January 14, 2026
The submission session is now available for: HORIZON-CL6-2026-02-FARM2FORK-09, HORIZON-CL6-2026-02-FARM2FORK-08, HORIZON-CL6-2026-02-FARM2FORK-02, HORIZON-CL6-2026-02-FARM2FORK-11, HORIZON-CL6-2026-02-FARM2FORK-01, HORIZON-CL6-2026-02-FARM2FORK-03, HORIZON-CL6-2026-02-FARM2FORK-10, HORIZON-CL6-2026-02-FARM2FORK-06, HORIZON-CL6-2026-02-FARM2FORK-13, HORIZON-CL6-2026-02-FARM2FORK-05, HORIZON-CL6-2026-02-CLIMATE-02, HORIZON-CL6-2026-02-CLIMATE-01, HORIZON-CL6-2026-02-FARM2FORK-12, HORIZON-CL6-2026-02-FARM2FORK-14, HORIZON-CL6-2026-02-FARM2FORK-07, HORIZON-CL6-2026-02-COMMUNITIES-01, HORIZON-CL6-2026-02-FARM2FORK-04
Grantalist - HORIZON-CL6-2026-02-FARM2FORK-12 - Leveraging R&i Knowledge On Microbiome | Grantalist