Closed

Industrial biotechnology approaches for improved sustainability and output of industrial bio-based processes

HORIZON Innovation Actions

Basic Information

Identifier
HORIZON-CL6-2023-ZEROPOLLUTION-01-5
Programme
Clean environment and zero pollution
Programme Period
2021 - 2027
Status
Closed (31094503)
Opening Date
December 22, 2022
Deadline
March 28, 2023
Deadline Model
single-stage
Budget
€8,000,000
Min Grant Amount
€4,000,000
Max Grant Amount
€4,000,000
Expected Number of Grants
2
Keywords
HORIZON-CL6-2023-ZEROPOLLUTION-01-5HORIZON-CL6-2023-ZEROPOLLUTION-01Agricultural biotechnologyAgriculture, Rural Development, FisheriesBiochemical research methodsBiological sciencesChemical sciencesEcology

Description

Expected Outcome:

A successful proposal will contribute to all Destination ‘’Zero pollution’ and in particular impacts related to enhancing circular bio-based systems to operate according to planetary boundaries, replacing fossil-based systems and their carbon footprint, mitigating climate change, restoring biodiversity and protecting air, water and soil quality along supply chain of biological feedstock and industrial value chains within the EU and Associated Countries and across borders. Furthermore, it will contribute by substituting harmful chemicals by safer, less toxic and generally more sustainable alternatives notably by boosting innovative biotechnology and other related technologies to create zero-pollution bio-based solutions.

Industrial biotechnology has a high potential to contribute to increased sustainability and in particular ‘zero pollution’ ambition of the European Green Deal, in respect to the (circular) industrial bio-based processes.

Project results are expected to contribute to all of the following outcomes:

  • Improved environmental sustainability, especially in terms of reduced toxicity, and overall safety to live organisms and ecosystems, of industrial bio-based processes, and of chemical and materials outputs, aligned with the EU climate-goals and zero-pollution ambition of the European Green Deal, in particular by lowering the input requirements in terms of e.g., land use, (virgin) feedstocks, water and energy, and by general advancement of non-toxic / zero-pollution production processes with positive impacts on water, air and soil quality.
  • Improved industrial competitiveness by developing scalable, flexible and robust multi-product manufacturing, responding to current trends in the industrial biotechnology (e.g., on-demand production, small-volume outputs, lower capital expenditure, digital / artificial intelligence (AI) solutions, lower/minimal dependence on scarce natural resources, especially in terms of biological feedstocks), ensuring links to EU / Associated Countries industrial ecosystems (SMEs, EU Partnerships such as Circular Bio-based Europe JU).
  • Enhanced social engagement and understanding of advanced bio-based innovation and in particular biotechnology among broad sectors of society, with active social innovation supported via dialogue with e.g., NGOs, end-user and consumer groups, schools or science centres etc.

Enhanced market up-take linked to improved governance[1] enabled by dialogue with regulatory actors and supporting networks, and by improved public awareness.

Scope:
  • The scope covers a wide array of biotechnology techniques, including targeted and specific approaches for DNA modification, including synthetic engineering at gene or genome level, in line with the binding regulatory requirements, including related necessary technical aspects in other fields, such as synthetic biology, cell sorting, automation, robotics, IT data/digital/AI innovations, or the ‘biofoundry’ concept[2], [3]. Approaches based on improved enzymatic solutions should carefully consider a parallel topic[4], to avoid overlaps, and create synergies.
  • Environmental improvements, especially reduced pollution/toxicity and lowered impacts should be verified and demonstrated by established methodology of life cycle assessment, and the monitoring approaches throughout the project need to be clearly established.
  • Production of biofuels and bioenergy is excluded from scope, to avoid overlaps with Horizon Europe Cluster 5. Health applications need to be carefully considered to avoid possible overlaps with activities supported under Horizon Europe Cluster 1.
  • Clear communication and dissemination activities are an essential element, including awareness raising, engagement of societal actors (NGOs, consumer organisations, professional organisations). Proposals should include a dedicated task, appropriate resources and a plan on how they will collaborate with other projects funded under this topic and other relevant topics.
  • International cooperation options may be considered, for win-win cooperation, and pursued if contributing to the European industrial competitiveness.
  • In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content is not a mandatory requirement.

[1] See parallel topic HORIZON-CL6-2023-GOVERNANCE-01-6: Co-creation and trust-building measures for biotechnology and bio-based innovation systems.

[2] http://www.weforum.org/agenda/2019/10/biofoundries-the-new-factories-for-genetic-products/.

[3] http://www.oecd-ilibrary.org/sites/bd16d851-en/index.html?itemId=/content/component/bd16d851-en.

[4] HORIZON-CL6-2023-CIRCBIO-01-5: Broadening the spectrum of robust enzymes and microbial hosts in industrial biotechnology.

Destination & Scope

Anthropogenic pollution undermines the integrity of Earth’s ecosystems and severely affects natural resources essential for human life. Keeping our planet clean and our ecosystems healthy will not only help addressing the climate crisis but also help regenerate biodiversity, ensure the sustainability of primary production activities and safeguard the well-being of humankind. In line with the objectives of the European Green Deal and related initiatives targeting environmental challenges, particularly the EU zero pollution action plan, the 2030 climate target plan, and other relevant EU legislation, this destination seeks to halt and prevent pollution by focusing on:

  • removing pollution from fresh and marine waters, soils, air, including from nitrogen and phosphorus emissions;
  • substituting harmful chemicals;
  • improving the environmental sustainability and circularity of bio-based systems;
  • reducing environmental impacts of and pollution in food systems.

Synergies with other clusters (notably 1 for health issues and 5 for air pollution from urban sources), relevant destinations, missions (particularly ‘A Soil Deal for Europe’ and ‘Restore our Ocean and Waters by 2030’) and partnerships will be exploited.

Topics under the heading Halting pollution of air, soil and water aim to identify and demonstrate approaches to combat diffuse emissions of pollutants from land and other sources. In this context, keeping nitrogen (N) and phosphorus (P) cycles in balance is a major challenge. N and P flows from anthropogenic sources, mostly from excessive or inefficient input of fertilisers (manure, sewage sludge, etc.) in agriculture and from waste water treatments, currently exceed planetary boundaries. Their leaching and run-off negatively affect soil biodiversity, pH, organic matter concentration and carbon sequestration capacity, and cause the eutrophication of water bodies while ammonia and nitrous oxide emissions affect air quality and climate. As all environmental compartments are concerned, a systemic approach is needed to limit N/P emissions from different sources, and to bring N/P flows back within safe ecological boundaries, e.g. by improving the way fertilising products in agriculture are managed while taking into account regional conditions. Actions will include showcasing best practices to recover nutrients from secondary raw materials in order to produce alternative fertilisers and demonstrating pathways for regions to keep their N/P flows within ecological boundaries.

Topics under Protecting drinking water and managing urban water pollution seek to develop and demonstrate a comprehensive framework bringing together new innovative solutions and approaches to ensure drinking water is of a good quality, address urban water pollution and harmonise different policies and management approaches. Actions should explore solutions to increase the resilience of urban waste water systems, reducing the carbon footprint and emissions, improve resource efficiency and energy recovery, and limit risks from contaminants of emerging concern. An integrated strategy to harmonise and update monitoring with prioritisation for comprehensive control of urban water cycles should be developed by harnessing the potential of digital solutions.

Topics under Addressing pollution in seas and ocean strive to fill knowledge gaps about risks and impacts of pollution from contaminants of emerging concern in the marine environment (in particular pharmaceuticals and endocrine disruptors) including in the context of the changing marine environment due to changes in the climate system. They will further develop and test solutions for the integrated assessment and monitoring of the circulation and impacts of contaminants of emerging concern in the marine environment, in order to help implement EU policies and legislation, e.g. the Water Framework Directive and Marine Strategy Framework Directive. Actions should also explore the role of pollution in intensifying impacts related to climate change, including in the Arctic, resulting in solutions and strategies to help ecosystems and human communities adapt as regards the changes in the Arctic.

Topics under Increasing the environmental sustainability and circularity of bio-based processes and products look at developing bio-based solutions for environmental monitoring and remediation as well as the concept of integrating sustainability and circularity into bio-based systems. This concept also includes bio-based chemicals, additives and materials solutions contributing to carbon removal objectives, the chemicals strategy for sustainability (CSS strategy) and the development of safe- and -sustainable-by-design materials and products.

Furthermore, topics under the heading Reducing the environmental impact and pollution of food systems focus on increasing our knowledge of the soil, water and air pollution stemming from different food production and supply practices and providing opportunities to reduce environmental and climate impacts of food systems. This also includes preventing and reducing plastic pollution stemming from plastic food packaging.

Expected impact

Proposals for topics under this destination should set out a credible pathway that helps to halt and eliminate pollution to guarantee clean and healthy soils, air, fresh and marine water for all and ensure that natural resources are used and managed in a sustainable and circular manner. To reach this objective, it will be vital to advance the knowledge of pollution sources and pathways to enable preventive measures to be rolled out, improve sustainability and circularity, apply planetary boundaries in practice and introduce effective remediation methods. To this end, the following is required:

  • move towards achieving clean, unpolluted surface water and groundwater bodies in the EU and Associated Countries by increasing understanding of diffuse and point sources of water pollution in a global and climate change context, enabling novel solutions to avoid degradation and restore water bodies, aquatic ecosystems and soil functionality, and further improve the quality and management of water for safe human and ecological use, while strengthening the EU’s and Associated Countries’ positions and roles in the global water scene;
  • balance N/P flows within safe ecological boundaries at regional and local level, helping restore ecosystems;
  • move towards achieving clean, unpolluted oceans and seas, including in the Arctic, by means of successful scientific, technological, behavioural, socio-economic, governance and green-blue transitions;
  • strengthen circular bio-based systems to operate within planetary boundaries, replacing fossil-based systems and their carbon footprint, mitigating climate change, and restoring biodiversity and protecting air, water and soil quality along the supply chain of biological feedstocks and industrial value chains within the EU and Associated Countries and across borders;
  • substitute harmful chemicals for safer and more sustainable alternatives, notably by boosting innovative biotechnology and other sustainable technologies to create zero-pollution bio-based solutions;
  • reduce the environmental impact of food systems, e.g. by increasing knowledge of the environmental and climate impacts stemming from the food systems and reducing pollution from plastic food packaging.

Eligibility & Conditions

General conditions

General conditions

1. Admissibility conditions: described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes

Proposal page limits and layout: described in Part B of the Application Form available in the Submission System

2. Eligible countries: described in Annex B of the Work Programme General Annexes

A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.

3. Other eligibility conditions: described in Annex B of the Work Programme General Annexes

4. Financial and operational capacity and exclusion: described in Annex C of the Work Programme General Annexes

  • Award criteria, scoring and thresholds are described in Annex D of the Work Programme General Annexes

  • Submission and evaluation processes are described in Annex F of the Work Programme General Annexes and the Online Manual

  • Indicative timeline for evaluation and grant agreement: described in Annex F of the Work Programme General Annexes

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025). [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf]].

6. Legal and financial set-up of the grants: described in Annex G of the Work Programme General Annexes

 

Specific conditions

7. Specific conditions: described in the [specific topic of the Work Programme]

 

Support & Resources

Online Manual is your guide on the procedures from proposal submission to managing your grant.

Horizon Europe Programme Guide contains the detailed guidance to the structure, budget and political priorities of Horizon Europe.

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The European Charter for Researchers and the Code of Conduct for their recruitment – consult the general principles and requirements specifying the roles, responsibilities and entitlements of researchers, employers and funders of researchers.

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Latest Updates

Last Changed: July 13, 2023

CALL UPDATE: FLASH EVALUATION RESULTS

 

EVALUATION results

Deadline: 28/03/2023

 

Topic Identifier

 Budget

HORIZON-CL6-2023-ZEROPOLLUTION-01-3

 €                12,000,000.00

HORIZON-CL6-2023-ZEROPOLLUTION-01-1

 €                  6,000,000.00

HORIZON-CL6-2023-ZEROPOLLUTION-01-2

 €                12,500,000.00

HORIZON-CL6-2023-ZEROPOLLUTION-01-5

 €                10,000,000.00

HORIZON-CL6-2023-ZEROPOLLUTION-01-6

 €                  8,000,000.00

HORIZON-CL6-2023-ZEROPOLLUTION-01-7

 €                  8,000,000.00

HORIZON-CL6-2023-ZEROPOLLUTION-01-4

 €                  8,000,000.00

 

The results of the evaluation are as follows:

Topic Id

Number of proposals submitted (including proposals transferred from or to other calls)

Number of inadmissible proposals

Number of ineligible proposals

Number of above-threshold proposals

Total budget requested for above-threshold proposals

HORIZON-CL6-2023-ZEROPOLLUTION-01-1

14

0

0

10

 €                  57,449,736.25

HORIZON-CL6-2023-ZEROPOLLUTION-01-2

10

0

0

5

 €                  31,185,909.50

HORIZON-CL6-2023-ZEROPOLLUTION-01-3

5

0

0

3

 €                  18,173,415.00

HORIZON-CL6-2023-ZEROPOLLUTION-01-4

7

0

0

5

 €                  19,398,647.75

HORIZON-CL6-2023-ZEROPOLLUTION-01-5

1

0

0

1

 €                    4,765,581.00

HORIZON-CL6-2023-ZEROPOLLUTION-01-6

11

0

1

8

 €                  32,289,161.26

HORIZON-CL6-2023-ZEROPOLLUTION-01-7

12

0

1

8

 €                  31,746,005.25

 

We recently informed the applicants about the evaluation results for their proposals.

For questions, please contact the Research Enquiry Service.

Last Changed: April 3, 2023

CALL UPDATE: PROPOSAL NUMBERS

 

PROPOSAL NUMBERS

Call HORIZON-CL6-2023-ZEROPOLLUTION-01 has closed on the on March 28.

60 proposals have been submitted.

The breakdown per topic is:

Topic Id

Proposals Received

HORIZON-CL6-2023-ZEROPOLLUTION-01-1

14

HORIZON-CL6-2023-ZEROPOLLUTION-01-2

10

HORIZON-CL6-2023-ZEROPOLLUTION-01-3

5

HORIZON-CL6-2023-ZEROPOLLUTION-01-4

7

HORIZON-CL6-2023-ZEROPOLLUTION-01-5

1

HORIZON-CL6-2023-ZEROPOLLUTION-01-6

11

HORIZON-CL6-2023-ZEROPOLLUTION-01-7

12

 

Evaluation results are expected to be communicated in July 2023



Last Changed: December 22, 2022
The submission session is now available for: HORIZON-CL6-2023-ZEROPOLLUTION-01-3(HORIZON-RIA), HORIZON-CL6-2023-ZEROPOLLUTION-01-4(HORIZON-RIA), HORIZON-CL6-2023-ZEROPOLLUTION-01-7(HORIZON-RIA), HORIZON-CL6-2023-ZEROPOLLUTION-01-1(HORIZON-RIA), HORIZON-CL6-2023-ZEROPOLLUTION-01-2(HORIZON-RIA), HORIZON-CL6-2023-ZEROPOLLUTION-01-6(HORIZON-RIA), HORIZON-CL6-2023-ZEROPOLLUTION-01-5(HORIZON-IA)
Industrial biotechnology approaches for improved sustainability and output of industrial bio-based processes | Grantalist