Closed

Photosynthesis revisited: climate emergency, “no pollution and zero-emission” challenge and industrial application

HORIZON Research and Innovation Actions

Basic Information

Identifier
HORIZON-CL6-2022-CIRCBIO-02-04-two-stage
Programme
Circular economy and bioeconomy sectors
Programme Period
2021 - 2027
Status
Closed (31094503)
Opening Date
October 28, 2021
Deadline
February 15, 2022
Deadline Model
two-stage
Budget
€21,000,000
Keywords
Artificial IntelligenceInternational CooperationDigital Agendabiotechnologyindustrial biomassmolecular biologybiodiversitysynthetic biologyhigh-value productphotoautotrophicozone pollutionbioeconomybio-basedclimate penaiity

Description

ExpectedOutcome:

The successful proposal will contribute to Destination ‘Circular economy and bioeconomy sectors’ impacts, and the European policies it supports, in particular the European Green Deal, the circular economy action plan and the bioeconomy strategy. They will help improve European industrial[1] sustainability, competitiveness and resource independence to develop innovative bio-based products. They will engage all stakeholders and improve their knowledge and understanding of science, notably of biotechnology-based value chains, and improve benefits for consumers.

Projects results should contribute to all of the following expected outcomes:

  • Wider application of recent advances in molecular biology and biotechnology to increase photosynthetic efficiency of plants and/or algae and other autotrophic organisms, increasing their assimilation of carbon dioxide, boosting biomass yields, their processing and recovery of substance and materials of economic interest, and resulting in potential contribution to climate change mitigation and adaptation.
  • Increased industrial uptake of plants and photoautotrophic organisms via biotechnology approaches, for the production of high-value complex molecules, to improve cost- and resource-efficiency. Wider uptake of life sciences and biotechnology innovations, supporting high engagement of industry and SMEs in Europe.
  • Greater understanding and application of biotechnology to address air pollution (especially ozone) by crops and plants related with heat waves and environmental stress.
  • Greater and more inclusive understanding and awareness of innovations, via transparent communication and societal dialogue with all stakeholders (academia, industry, SMEs, NGOs, regulatory institutions, international partners etc.).
Scope:

The photosynthetic capacity of plants, algae and other photosynthetic organisms to assimilate atmospheric carbon dioxide positions them at the centre of the global climate change adaptation and mitigation challenge[2] [3]. Their autotrophic lifestyle also makes them ideal platform organisms for sustainable production of biomolecules[4], including molecules of high socio-economic value, of interest to diverse industrial sectors, by increasingly sophisticated synthetic and molecular biology approaches[5].

This creates new opportunities for industrial production, beyond improved yields, while helping increase CO2 assimilation capacity - contributing notably to the reduction of pollution in Europe, and making it more efficient. In particular, recent research confirm a strong correlation between plant physiological reactions during drought and heat waves, which are increasing in frequency and intensity in Europe, notably by contributing to ozone pollution[6], the so-called ‘climate penalty of plants” [7] [8].

The topic covers innovative technologies with potential to boost the efficiency of photosynthesis, reduce the ‘climate penalty of plants’, and increase their sustainable industrial application. All photoautotrophic organisms such as plants, micro- and macro algae, cyanobacteria and purple sulphur bacteria are in the scope.

International cooperation is strongly encouraged to allow the exchange of best practices while ensuring win-win scenarios and contributing to European competitiveness.

Proposals should:

  1. Develop and apply a toolbox of technologies to optimise the photosynthesis pathways and structures of plants and algae to enable industrial manufacturing of large quantities of high-value bio-based compounds, substances or materials (excluding biofuels/bioenergy applications), while addressing the CO2 assimilation and the zero-pollution goals (especially ozone pollution) at sufficiently large scale.
  2. Identify and characterise the key aspects of the environmental and safety aspects, as well as the future scenarios of increasing environmental pressures under climate change conditions (water, gaseous inputs, land use etc.), for the selected crops, beyond the model species.
  3. Outline the necessary scale-up production processes for novel bio-based innovations in order to reach a critical mass for a given application (including the crop/species selection), to achieve economies of scale, address different market segments and applications.
  4. Consider process and product safety - including the occupational and consumer safety aspects - in value chains, in line with national or European regulationsEnsure the transparent and inclusive engagement of all actors, including industry and SMEs, the scientific community, regulatory institutions, and broader civil society, including NGOs, to ensure the necessary impact and awareness.
  5. Where relevant, proposals should seek links with and capitalise on the results of past [9] and ongoing [10] research projects, taking care to avoid overlaps.

For this topic, it is not mandatory to integrate the gender dimension (sex and gender analysis) into research and innovation.

Specific Topic Conditions:

Activities are expected to achieve TRL 4-5 by the end of the project – see General Annex B.

Cross-cutting Priorities:

Digital Agenda
Artificial Intelligence
International Cooperation

[1]In connection with European partnerships under Cluster 6, in particular Circular Bio-based Europe (CBE).

[2]For instance, see Ort et al. Redesigning photosynthesis to sustainably meet global food and bioenergy demand. Proc. Natl Acad. Sci. USA112, 8529–8536 (2015).

[3]Notwithstanding the recognized need for even stronger emission reductions.

[4] O’Neill E. and Kelly, S. 2016 Engineering biosynthesis of high-value compounds in photosynthetic organisms,

[5]Schander et al., A synthetic pathway for the fixation of carbon dioxide in vitro, Science 18 (Nov 2016): 900-904

[6]Lin et al.Vegetation feedbacks during drought exacerbate ozone air pollution extremes in Europe. Nat. Clim. Chang.10, 444–451 (2020). https://doi.org/10.1038/s41558-020-0743-y

[7]Sadiq, M. The climate penalty of plants. Nat. Clim. Chang.10, 387–388 (2020). https://doi.org/10.1038/s41558-020-0765-5

[8]Air quality in Europe – 2019 report Report no. 10/2019 (European Environment Agency, 2019); https://www.eea.europa.eu//publications/air-quality-in-europe-2019

[9] E.g. FP7 project “3to4”: Converting C3 to C4 photosynthesis for sustainable agriculture

[10] E.g. Horizon 2020 call BIOTEC-02-2019: Boosting the efficiency of photosynthesis (RIA), with projects CAPITALISE, GAIN4CROPS and PhotoBoost.

Destination & Scope

This destination and its topics target climate-neutral circular and bioeconomy transitions, covering safe integrated circular solutions at territorial and sectoral levels, for important material flows and product value chains, such as the textile, electronics, plastics and construction sectors, as well as key bioeconomy sectors such as sustainable bio-based systems, sustainable forestry, small-scale rural bio-based solutions, and aquatic value chains. With this approach, the destination supports the European Green Deal, and other European initiatives such as the Industrial Strategy, SME Strategy, Circular Economy Action Plan, Bioeconomy Strategy, Biodiversity Strategy, Farm to Fork Strategy, Textile Strategy, Plastics Strategy, the Action Plan on Critical Raw Materials, and the Forest Strategy.

More specifically, the focus on circularity[[In synergy with Horizon Europe Clusters 4 and 5, in particular, Cluster 4 dealing with industrial and technological aspects and raw materials supply, including construction with lower environmental footprint, through modularisation, digital technologies, circularity and advanced materials, while Cluster 6 has a systemic approach across sectors including civil society, covering the whole value chain: including technological, business, governance and social innovation aspects. ]] aims at less waste and more value by extending the lifetime and retaining the value of products and materials. It supports a sharing, reusing, and material-efficient economy, in a safe way, and minimises the non-sustainable use of natural resources. The cascading use of materials and innovative upcycling of waste to new applications is encouraged. The safe and sustainable use of biomass and waste[[EU Waste Framework legislation: https://ec.europa.eu/environment/waste/legislation/]] for the production of materials and products, including nutrients, can reduce Europe’s dependence on non-renewable resources, cut GHG emissions, offer long-term circular carbon sinks and substitutes to fossil-based and carbon-intensive products, and reduce pressures on biodiversity and its wide range of ecosystem services. The potential of biological resources goes beyond biomass processing into renewable products. It includes the use of organisms and their parts in “green” (i.e. more environmentally friendly) bio-based industrial processes. Marine and land-based biotechnology can provide new sustainable and safe food and feed production methods, greener industrial products and processes, new health-related products, and can help characterise, monitor and sustain the health of marine and terrestrial ecosystems. The potential of marine resources and biotechnology will contribute to the coming “blue economy”, accelerating the transition towards a circular and climate-neutral economy that is sustainable and inclusive. The concepts of the circular economy, bioeconomy and blue economy converge and altogether provide an opportunity to balance environmental, social and economic goals, with their sustainability ensured by the life cycle assessment approaches.

Acknowledging the multiple benefits of circularized material/substance and energy flows, such circularity however has to be achieved in a safe, non-hazardous way without (re-)connecting epidemiological pathways or introducing pathogen/toxin enrichment cycles when involving biogenic materials. Established circularized material/substance flows have to be complemented with accompanying research in their safety and non-hazardous to health, society, economy and nature. In addition, a local and regional focus[[In synergy with Horizon Europe Cluster 4, with focus on the industrial dimensions; and Cluster 5, covering cross-sectoral solutions for decarbonisation (including on community level), whereas Cluster 6 targets systemic regional and local (i.e. territorial) circular and bioeconomy approach.]] is crucial for a circular economy and bioeconomy that is sustainable, regenerative, inclusive and just. Innovative urban and regional solutions and value chains can create more and better quality jobs and help our economies rebound from the COVID-19 crisis.

A systemic and science-based circular transition with the help of research, innovation and investments will address all issues from material selection and product design via resource efficiency along the value chain to an optimised after-use system, incorporating reuse, repair and upgrade, refurbishment, remanufacturing, collection, sorting and new forms of recycling and upcycling also to improve the waste cycle management. It will tackle all barriers and mobilise all key stakeholders. The development of definitions, taxonomies, indicators and targets will inform and support policy and decision making. The use of advanced life cycle methods such as the European Commission Product Environmental Footprint (PEF), data and information will enable economic actors, including consumers, to make sustainable choices. The development and deployment of specific technological and non-technological circular solutions, including new business models, will cover intra- and inter-value chain collaboration between economic actors. The development of a working after-use system for plastic-based products, incorporating reuse, collection, sorting, and recycling technologies will provide insights into the transition towards a circular economy for key material flows including plastics. The Circular Cities and Regions Initiative (CCRI)[[https://ec.europa.eu/research/environment/index.cfm?pg=circular]] under the European Circular Economy Action Plan will expand the circular economy concept beyond traditional resource recovery in waste and water sectors and support the implementation, demonstration and replication of systemic circular solutions for the transition towards a sustainable, regenerative, inclusive and just circular economy at local and regional scale. Water use will be tackled from a circularity perspective, aiming at pollution prevention, resource efficiency and business opportunities.

Bio-based innovation lays the foundations for the transition away from a fossil-based carbon-intensive economy by encompassing the sustainable sourcing, industrial[[In synergy with Horizon Europe Clusters 4, 5 (including their European Partnerships), whereas Cluster 4 targets industrial dimension (including digitisation and circular and climate neutral / low carbon industry, including developing bio-integrated manufacturing), and Cluster 5 covers cost-efficient, net zero-greenhouse gas energy system centred on renewables (including R&D necessary to reduce CO2 emissions from the power and energy-intensive industry sector, solutions for capturing, utilisation and storage of CO2 (CCUS), and bioenergy and other industrial sectors), while Cluster 6 covers the research and innovation based on sustainable biological resources (bioeconomy sectors), in particular for new sustainable feedstock development and through the development of integrated bio-refineries).]][[In synergy with the European Partnership on Circular Bio-based Europe (CBE), under Horizon Europe Cluster 6.]] and small scale processing and conversion of biomass from land and sea into circular bio-based materials and products with reduced carbon and environmental footprint including lower impacts on biodiversity and long-term circular carbon sinks in sustainable products substituting carbon-intensive ones, with improved end-of-life including biodegradability in specific natural as well as controlled environments. It also capitalises on the potential of living resources, life sciences and industrial biotechnology for new discoveries, products, services and processes, both terrestrial and marine. Bio-based innovation can bring new and competitive economic activities and employment to regions and cities in the recovery from the COVID-19 crisis, revitalising urban, rural and coastal economies and strengthening the long-term circularity of the bioeconomy, including through small non-food bio-based solutions. Furthermore, targeted and well-tailored investments can increase and diversify the income of primary producers and other rural actors (e.g. SMEs).

To enable the bio-based innovation, environmental objectives and climate neutrality will build on a robust understanding of environmental impacts and trade-offs of bio-based systems at the European and regional scale, including the comparisons to similar aspects on the fossil and carbon-intensive counterparts. Systemic impacts of bio-based systems on biodiversity and its wide range of ecosystem services as well as how we restore and use them, need to be assessed, and negative impacts avoided in line with the “do no harm” principle of the European Green Deal. Implementing sustainable and just bio-based value chain requires symbiosis across primary production and industrial ecosystems in regions, Member States and Associated Countries and improved environmental performance of products, processes, materials and services along value chains and life cycles.

The multifunctional and sustainable management of European forests as well as the environmentally sustainable use of wood and woody biomass as a raw material have a crucial role to play in the achievement of the EU’s climate and energy policies, the transition to a circular and sustainable bioeconomy as well as the preservation of biodiversity and the provision of ecosystem services such as climate regulation, recreation, clean air, water resources and erosion control among many others. Furthermore, forestry and the forest-based sector offer important opportunities for wealth and job creation in rural, peripheral and urban areas. The condition of European forests is increasingly threatened by a growing number of social, economic and environmental and climatic pressures. The European Green Deal and the EU Biodiversity Strategy for 2030 recognise that the EU’s forested area needs to improve, both in quality and quantity, for the EU to reach climate neutrality and a healthy environment. The multifunctionality and the sustainable forest management under rapid climate change will be enabled through a variety of approaches, including the use of intelligent digital solutions, enhanced cooperation in forestry and the forest-based sector as well as the establishment of an open-innovation ecosystem with relevant stakeholders.

Aquatic biological resources and blue biotechnology are crucial to delivering on the Green Deal’s ambition of a ‘blue economy’, which alleviates the multiple demands on the EU's and the Associated Countries’ land resources and tackles climate change.

The immense marine and freshwater biodiversity both faces and offers solutions to multiple challenges such as climate, biodiversity loss, pollution, food security, green products, and health but remains largely unexplored. Unprecedented advances in the biotechnology toolbox (e.g. -omics, bioinformatics, synthetic biology) have triggered an increased interest in the potential of aquatic bioresources. Further research and innovation will be key to unlocking the value of the marine and freshwater biological resources available in Europe, including its outermost regions by learning from the functioning and processes of aquatic living organisms to provide a sustainable products and services to the society, whilst avoiding systemic impacts on biodiversity. Algae biomass is becoming increasingly important not only as food but also as a sustainable source of blue bioeconomy products such as pharmaceuticals, cosmetics, and speciality chemicals. Although only a small fraction of marine microbial diversity has been characterised to date, advances in genetic and sequencing technologies are opening new avenues for the understanding and harnessing marine microbiomes such as for the biodiscovery of new products and services for the environment and society.

Expected impacts

Proposals for topics under this destination should set out a credible pathway to developing circular economy and bioeconomy sectors, achieving sustainable and circular management and use of natural resources, as well as prevention and removal of pollution, unlocking the full potential and benefits of the circular economy and the bioeconomy, ensuring competitiveness and guaranteeing healthy soil, air, fresh and marine water for all, through better understanding of planetary boundaries and wide deployment and market uptake of innovative technologies and other solutions, notably in primary production (forestry) and bio-based systems.

Specifically, the topics will target one or several of the following impacts, for circular economy, bio-based sectors, forestry and aquatic value chains:

  • Regional, rural, local/urban and consumer-based transitions towards a sustainable, regenerative, inclusive and just circular economy and bioeconomy across all regions of Europe based on enhanced knowledge and understanding of science, in particular regarding biotechnology-based value chains, for all actors, including policy makers, to design, implement and monitor policies and instruments for a circular and bio-based transitions.
  • European industrial sustainability, competitiveness and resource independence by lowering the use of primary non-renewable raw materials and reducing greenhouse gas emissions and other negative environmental footprint (including on biodiversity), enabling climate-neutrality and higher resource efficiency (e.g. by circular design, improved waste management, cascading use of biomass) along and across value chains, developing innovative and sustainable value-chains in the bio-based sectors, substituting fossil-based ones, increasing circular practices in textiles, plastics, electronics and construction, developing recycling technologies and industrial symbiosis, increasing circular bio-based systems from sustainably sourced biological resources replacing carbon-intensive and fossil-based systems, with inclusive engagement of all stakeholders;
  • Improved consumer and citizen benefits, including in the rural settings by establishing circular and bio-based systems based on sustainability, inclusiveness, health and safety; reaching a significantly higher level of involvement of all actors (manufacturers, retailers, consumers, public administration, primary biomass producers etc.);
  • Multi-functionality and management of forests in Europe based on the three pillars of sustainability (economic, environmental and social);
  • Enlarged potential of marine and freshwater biological resources and blue biotechnology to deliver greener (climate-neutral circular) industrial products and processes, and to help characterise, monitor and sustain the health of aquatic ecosystems for a healthy planet and people.

When considering their impact, proposals also need to assess their compliance with the “Do No Significant Harm” principle[[as per Article 17 of Regulation (EU) No 2020/852 on the establishment of a framework to facilitate sustainable investment (EU Taxonomy Regulation)]] according to which the research and innovation activities of the project should not be supporting or carrying out activities that make a significant harm to any of the six environmental objectives of the EU Taxonomy Regulation.

In addition to the impacts listed above, topics under this destination will address the following impact areas of the Horizon Europe Strategic Plan for 2021-2024: “Climate change mitigation and adaptation”, “Enhancing ecosystems and biodiversity on land and in waters”, “A resilient EU prepared for emerging threats”; “Inclusive growth and new job opportunities”; “Industrial leadership in key and emerging technologies that work for people”.

Eligibility & Conditions

General conditions

1. Admissibility conditions: described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes

 

 

Proposal page limits and layout: described in Part B of the Application Form available in the Submission System

 

 

2. Eligible countries: described in Annex B of the Work Programme General Annexes

A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.

 

3. Other eligibility conditions: described in Annex B of the Work Programme General Annexes

 

 

4. Financial and operational capacity and exclusion: described in Annex C of the Work Programme General Annexes

 

 

5. Evaluation and award:

 

  • Award criteria, scoring and thresholds are described in Annex D of the Work Programme General Annexes
  • Submission and evaluation processes are described in Annex F of the Work Programme General Annexes and the Online Manual
  • Indicative timeline for evaluation and grant agreement: described in Annex F of the Work Programme General Annexes

 

6. Legal and financial set-up of the grants: described in Annex G of the Work Programme General Annexes

 

Specific conditions

7. Specific conditions: described in the [specific topic of the Work Programme]

 

Documents

Call documents:

Standard application form — call-specific application form is available in the Submission System

Standard application form (HE RIA, IA)

Standard evaluation form will be used with the necessary adaptations

Standard evaluation form (HE RIA, IA)

MGA

HE General MGA v1.0

 

Additional documents:

HE Main Work Programme 2021–2022 – 1. General Introduction

HE Main Work Programme 2021–2022 – 9. Food, Bioeconomy, Natural Resources, Agriculture and Environment

HE Main Work Programme 2021–2022 – 13. General Annexes

HE Programme Guide

HE Framework Programme and Rules for Participation Regulation 2021/695

HE Specific Programme Decision 2021/764

EU Financial Regulation

Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment

EU Grants AGA — Annotated Model Grant Agreement

Funding & Tenders Portal Online Manual

Funding & Tenders Portal Terms and Conditions

Funding & Tenders Portal Privacy Statement

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Latest Updates

Last Changed: May 25, 2022

 

CALL UPDATE: GENERALISED FEEDBACK AFTER STAGE 1

 

GENERALISED FEEDBACK for successful applicants after STAGE 1

In order to best ensure equal treatment, successful stage 1 applicants do not receive the Evaluation Summary Reports (ESRs) for their proposals, but this generalised feedback with information and tips for preparing the full proposal. 

Information & tips Shortcomings/minor shortcomings found in proposals of stage-1 evaluation of HORIZON-CL6-2022-CircBio-02-04-two-stage:

·         For some proposals, some innovation aspects and how the proposal advances beyond the state of the art are insufficiently demonstrated. In particular, how proposals differ from the recently funded EU projects is not always sufficiently well described.

·         For some proposals, the methodology lacked details to explain how negative effects would be addressed and to further support how realistic the positive effects would be.

·         Some proposals insufficiently explain how inputs from citizens, civil society and end users would be taken into account.

·         For some proposals, the necessity to produce engineered strains is insufficiently demonstrated.

·         Proposals do not always address in sufficient details the scale and significance of the proposal’s contribution to each expected outcomes (topic level) and targeted expected impacts (at the level of the destination).

·         Some proposals do not sufficiently provide plausible and measurable and targets of the proposal’s contribution to expected outcomes and impacts.

·         Some proposals do not explicitly address the pathways of their contribution to destination’s impact.

·         Potential barriers to achieve the expected outcomes and impacts are not always addressed specifically enough. In particular most proposals insufficiently considers beforehand the barriers related to GMO's risk posed to the environment, biodiversity conservation, ethics and human health and their necessary legal authorization.

In your stage 2 proposal, you have a chance to address or clarify these issues.

Please bear in mind that your full proposal will now be evaluated more in-depth and possibly by a new group of outside experts.

Please make sure that your full proposal is consistent with your short outline proposal. It may NOT differ substantially. The project must stay the same.

Photosynthesis revisited: climate emergency, “no pollution and zero-emission” challenge and industrial application | Grantalist