Closed

Physical and cognitive augmentation in advanced manufacturing (Made in Europe Partnership) (RIA)

HORIZON Research and Innovation Actions

Basic Information

Identifier
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02
Programme
INDUSTRY
Programme Period
2021 - 2027
Status
Closed (31094503)
Opening Date
May 22, 2025
Deadline
September 23, 2025
Deadline Model
single-stage
Budget
€15,000,000
Min Grant Amount
€4,000,000
Max Grant Amount
€5,000,000
Expected Number of Grants
3
Keywords
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02HORIZON-CL4-2025-01

Description

Expected Outcome:

Manufacturing industry should benefit from the following outcomes:

  • Empower workers at all levels in factories, both individuals and teams, through breakthrough augmentation technologies embodying the next stage in human-machine interactions;
  • Enhance, with the help of these technologies and related contributions from Social Sciences and Humanities (SSH), the flexibility, inclusiveness, safety and well-being of workers in the industrial environment, leading to more attractive jobs in the EU, attracting and retaining talents from new generations (e.g. Generation Z);
  • Foster the human-centric aspect of the Industry 5.0 model, through insights into how technology affects the working environment and the organisation, and into how technology can support the worker in their career (including the associated meaningful job profiles).
Scope:

The rising complexity of discrete manufacturing operations requires workers to adapt to the introduction of new breakthrough technologies, machines, processes, and production environments (considering where appropriate legacy machinery). In addition, labour shortages are growing. The development of a human-centric culture that places the humans at the centre of the manufacturing operation is crucial. Augmentation technologies support and empower the workforce, leading to more high-quality jobs and prosperity beyond efficiency. They can relieve people of non-creative tasks or reduce human strain and stress and potential risks in the workplace. Augmentation technologies can therefore produce benefits for both workers and managers and can become the most effective ways of supporting, or amplifying, human abilities.

Proposals should develop breakthrough technologies to augment human capabilities and skills. Proposals should cover all of the following aspects:

  • Develop breakthrough solutions (based on e.g. mechatronics, sensing and photonics) for human-centric approaches; these include innovative perception technologies to sense the shopfloor environment and to predict the intentions of humans, also leading to enhanced worker safety and reduction of discomfort, fatigue and physical and psychological stress;
  • Develop innovative methodologies, potentially using AI, to provide reasoning capabilities and to control the behaviour of the manufacturing systems, to support humans and to interact and communicate with them; this will foster natural improvements in efficiency, sharing of knowledge, inclusiveness, accessibility and flexibility;
  • Assess and take into account the needs of managers and workers, at the beginning of the design phase and throughout all stages up to the development of a prototype, ensuring that both workers and managers have the right skills to implement the innovative solutions and that the solutions take into account the variety of workforces;
  • Develop new methodologies to perform an assessment of augmentation technologies and their suitability and value added (beyond economics) for workers in all their diversity.

Digital-twin models can be potentially used in the development of new assessment methodologies to perform validation in a virtual scenario.

The assessment methodologies may lead to new standards for the validation of the developed systems, or indicate how new or existing standards could benefit from a human-centric approach and how the developed systems could support this.

Proposals should take into account Social Sciences and Humanities (SSH) contributions regarding human-related barriers for the uptake of augmentation technologies in industrial environments, such as ergonomics, user experience, comfort, trust, feeling of safety, knowledge sharing and liability in modern production facilities. Proposals should specifically address gender, age, disability and other anthropometric and ergonomic considerations, and impacts across diverse demographic groups. Social partners (e.g. trade unions) may also be considered. Optionally, proposals may include test and experimentation environments such as living labs for validation.

Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination (adapted to the expected TRL of this topic).

This topic implements the co-programmed European Partnership Made in Europe.

Destination & Scope

The research and innovation under this Destination will continue to support a globally competitive European industry through the twin green and digital transition. The development of new and cross-cutting technologies will boost the transformation of existing value chains and the creation of new ones.

Supporting net-zero manufacturing is a key objective of the Net-Zero Industry Act and has a crucial role to play in the transition towards a green and sustainable society, going from ‘smart factory’ to a ‘smart sustainable value chain’. Smart manufacturing will help develop the materials and products needed to support net-zero and less polluting industries. There is much scope for improvement in circularity technologies applicable to different value chains, with special attention needed for product design, re-use, disassembly, remanufacturing/upgrading, recycling, and ‘Zero-X’ – zero defects, zero breakdowns and zero waste.

Digital technologies, like big data, advanced computing, and networking (including quantum), AI, robotics, photonics and the industrial virtual worlds will transform the practices of research, design and engineering, with better performing net-zero solutions and increased productivity in all sectors. Quick-response services can support hyperflexible production using, e.g. trustworthy AI and digital twins, with digitally enabled certification and qualification of processes and products.

In addition to decarbonisation, energy-intensive industries need to embrace the circular economy as a key pillar in the design of their value chains. This will be fundamental to their resource efficiency (in terms of materials, energy and water). Particularly important in this context is the innovative upcycling of secondary raw materials and waste and the development of sustainable and resource-efficient industrial processes.

The EU has set an ambitious goal for Europe to become the first climate-neutral continent by 2050. In some areas the key solutions for achieving significant reductions in emissions are already in the market. In crucial parts of the economy, as is the case for energy-intensive industries, many of the tools needed for such a significant reduction are still at an earlier stage of industrial or commercial development.

Further development and deployment of technologies identified in the ERA (European Research Area) industrial technology roadmaps for circular technologies and for low-carbon technologies will be essential to achieve this goal. Manufacturing processes, supply chains, cyber-physical systems or cities will become more climate neutral and less polluting, and circular solutions will include AI and digital twins, and the deployment of common European data spaces like those under the Digital Europe Programme.

Across industries, the human dimension (including gender differences) will be stressed via the Industry 5.0 paradigm.

To successfully move from innovation to deployment, a more effective transfer from small-scale industrial demonstrators to first-of-a-kind climate-neutral demonstrators is needed.

Business cases and exploitation strategies for industrialisation:

This section applies only to those topics in this Destination, for which proposals should demonstrate the expected outcomes by including a business case and exploitation strategy for industrialisation.

A business case and a credible initial exploitation strategy are essential components in the ultimate success of an industry-based project, as well as its prospects to attract further investments for deployment. They will both be decisive factors under the impact criterion, and proposers are encouraged to use the extended page limit to present a carefully considered business case and exploitation strategy, backed by the management of the companies involved.

The business case should demonstrate the expected impact of the proposal in terms of enhanced market opportunities for the participants and deployment in the EU, in the short to medium term. It should describe the targeted market(s); estimated market size in the EU and globally; user and customer needs; and demonstrate that the solutions will match the market and user needs in a cost-effective manner; and describe the expected market position and competitive advantage.

The exploitation strategy should identify obstacles, requirements and necessary actions involved in reaching higher TRLs (Technology Readiness Levels), for example: securing the required investments, including through possible synergies with other programmes; accessing the required skills; matching value chains; enhancing product robustness; securing industrial integrators; and user acceptance.

For TRLs 6 and 7, a credible strategy to achieve future full-scale deployment in the EU is expected, indicating the intentions of the industrial partners after the end of the project.

Where relevant, in the context of skills, it is recommended to develop training material to endow workers with the right skillset in order to support the uptake and deployment of new innovative products, services, and processes developed in the different projects. This material should be tested and be scalable, and can potentially be up-scaled through the European Social Fund Plus (ESF+). This will help the European labour force to close the skill gaps in the relevant sectors and occupational groups and improve employment and social levels across the EU and associated countries.

For topics in this destination, consortia (if selected for funding) could consider voluntary contributions in terms of data, indicators and knowledge to relevant Joint Research Centre (JRC) platforms for capitalising the knowledge developed in their projects and become more policy relevant:

Innovation Actions — Legal entities established in China are not eligible to participate in Innovation Actions in any capacity. Please refer to the Annex B of the General Annexes of this Work Programme for further details.

Eligibility & Conditions

General conditions

1. Admissibility Conditions: Proposal page limit and layout

described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.

Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.

2. Eligible Countries

described in Annex B of the Work Programme General Annexes.

A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.

3. Other Eligible Conditions

described in Annex B of the Work Programme General Annexes.

4. Financial and operational capacity and exclusion

described in Annex C of the Work Programme General Annexes.

5a. Evaluation and award: Award criteria, scoring and thresholds

are described in Annex D of the Work Programme General Annexes.

5b. Evaluation and award: Submission and evaluation processes

are described in Annex F of the Work Programme General Annexes and the Online Manual.

5c. Evaluation and award: Indicative timeline for evaluation and grant agreement

described in Annex F of the Work Programme General Annexes.

6. Legal and financial set-up of the grants

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025). [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf]].

described in Annex G of the Work Programme General Annexes.

Specific conditions

described in the [specific topic of the Work Programme]

Support & Resources

Online Manual is your guide on the procedures from proposal submission to managing your grant.

Horizon Europe Programme Guide contains the detailed guidance to the structure, budget and political priorities of Horizon Europe.

Funding & Tenders Portal FAQ – find the answers to most frequently asked questions on submission of proposals, evaluation and grant management.

Research Enquiry Service – ask questions about any aspect of European research in general and the EU Research Framework Programmes in particular.

National Contact Points (NCPs) – get guidance, practical information and assistance on participation in Horizon Europe. There are also NCPs in many non-EU and non-associated countries (‘third-countries’).

Enterprise Europe Network – contact your EEN national contact for advice to businesses with special focus on SMEs. The support includes guidance on the EU research funding.

IT Helpdesk – contact the Funding & Tenders Portal IT helpdesk for questions such as forgotten passwords, access rights and roles, technical aspects of submission of proposals, etc.

European IPR Helpdesk assists you on intellectual property issues.

CEN-CENELEC Research Helpdesk and ETSI Research Helpdesk – the European Standards Organisations advise you how to tackle standardisation in your project proposal.

The European Charter for Researchers and the Code of Conduct for their recruitment – consult the general principles and requirements specifying the roles, responsibilities and entitlements of researchers, employers and funders of researchers.

Partner Search help you find a partner organisation for your proposal.

Latest Updates

Last Changed: September 23, 2025

CALL UPDATE: PROPOSAL NUMBERS



Call HORIZON-CL4-2025-01 has closed on the 23/09/2025.

639 proposals have been submitted.



The breakdown per topic is:

Topic ID

Topic title

Action type

Proposals submitted

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-01

Integrated approaches for remanufacturing (Made in Europe Partnership) (IA)

IA

80

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02

Physical and cognitive augmentation in advanced manufacturing (Made in Europe Partnership) (RIA)

RIA

94

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-05

Advanced manufacturing technologies for leadership of EU manufacturers in products for the net-zero industry (Made in Europe Partnership) (IA)

IA

64

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-31

From heat-driven processes to the use of mechanical and electric forces (Processes4Planet Partnership) (IA)

IA

13

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-32

Green and resilient flexible production processes (Processes4Planet Partnership) (IA)

IA

19

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-33

Integrated use of renewable energy carriers in industrial sites (Processes4Planet Partnership) (RIA)

RIA

35

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-34

Smart integration of net zero technologies into Energy Intensive industries (Processes4Planet and Made in Europe Partnerships) (IA)

IA

12

TWIN-TRANSITION-36

Safe and clean processing technologies and products (Processes4Planet Partnership) (RIA)

RIA

25

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-37

Solving issues in carbon-neutral iron and steel making processes with diverse input materials of varying quality (Clean Steel Partnership) (RIA)

RIA

22

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-38

Synergies and mutual learning with national and regional initiatives in Europe on Industrial decarbonisation (Processes4Planet and Clean Steel Partnerships) (CSA)

CSA

1

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-39

Towards human-centric, sustainable and resilient energy-intensive industries (Processes4Planet and Clean Steel Partnerships) (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-31

Digitally enabled local-for-local textile and apparel production (Textiles for the Future Partnership) (IA)

IA

33

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-44

Innovative Advanced Materials Innovation Procurement (CSA)

CSA

4

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-45

Materials Commons for Europe (IA)

IA

3

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52

Accelerate the uptake of life-cycle assessment (LCA) for Safe and Sustainable by Design (SSbD) chemicals and materials and resulting products (RIA)

RIA

35

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-61

Technologies for critical raw materials and strategic raw materials from end-of-life products (IA)

IA

38

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-62

Strategic Partnerships for Raw Materials: Innovative approaches for sustainable production of Critical Raw Materials (IA)

IA

31

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-63

Innovative solutions for the sustainable production for semiconductor raw materials (IA)

IA

7

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-64

EU Co-funded Partnership on raw materials for the green and digital transition (Programme Co-fund action)

COFUND

1

HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61

AI Foundation models in science (GenAI4EU) (RIA)

RIA

47

HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62

Facilitated cooperation for AI in Science (CSA)

CSA

7

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-60

Horizon Standardisation Booster (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-61

Standardisation landscape analyses tool (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-62

Artificial Intelligence for knowledge valorisation (CSA)

CSA

15

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-63

Value creation pilots for scaling up innovative solutions (CSA)

CSA

10

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-64

Pilot initiatives on Technology Infrastructures (CSA)

CSA

20

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65

Network of Industry 5.0 system innovation hubs in connected Regional Innovation Valleys (IA)

IA

8

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-66

Assessment of Technology Infrastructure needs in Ukraine (CSA)

CSA

6

Total:

639



Evaluation results are expected to be communicated around mid-January 2026.



A.R.



Last Changed: September 15, 2025

Reminder on proposal part B page limit and formatting conditions



1.    Proposal part B page limit



The title, list of participants and sections 1, 2 and 3, together, should not be longer than page limit, indicated in a proposal part B template inside the Submission System. All tables, figures, references and any other element pertaining to these sections must be included as an integral part of these sections and are thus counted against this page limit.



The page limit will be applied automatically. At the end of a proposal part B template inside the Submission System you can see the structure of the actual proposal that you need to submit, please remove all instruction pages that are watermarked.



If you attempt to upload a proposal longer than the specified limit before the deadline, you will receive an automatic warning and will be advised to shorten and re-upload the proposal. After the deadline, excess pages (in over-long proposals/applications) will be automatically made invisible, and will not be taken into consideration by the experts. The proposal is a self-contained document. Experts will be instructed to ignore hyperlinks to information that is specifically designed to expand the proposal, thus circumventing the page limit.



Please, do not consider the page limit as a target! It is in your interest to keep your text as concise as possible, since experts rarely view unnecessarily long proposals in a positive light.



2.Proposal part B formatting conditions



The following formatting conditions apply (as listed in a proposal part B template inside the Submission System) and will be checked by the Agency during an admissibility check of submitted proposals.



The reference font for the body text of proposals is Times New Roman (Windows platforms), Times/Times New Roman (Apple platforms) or Nimbus Roman No. 9 L (Linux distributions).

The use of a different font for the body text is not advised and is subject to the cumulative conditions that the font is legible and that its use does not significantly shorten the representation of the proposal in number of pages compared to using the reference font (for example with a view to bypass the page limit).



The minimum font size allowed is 11 points. Standard character spacing and a minimum of single line spacing is to be used. This applies to the body text, including text in tables.



Text elements other than the body text, such as headers, foot/end notes, captions, formula's, may deviate, but must be legible.



The page size is A4, and all margins (top, bottom, left, right) should be at least 15 mm (not including any footers or headers).



Proposal part B template inside the Submission System document is tagged. Do not delete the tags; they are needed for our internal processing of information, mostly for statistical gathering. In that light, please do not move, delete, re-order, alter tags in any way, as they might create problems in our internal processing tools. Tags do not affect or influence the outcome of your application.



Last Changed: June 10, 2025

Please note that due to a technical issue, during the first days of publication of this call, the topic page did not display the description of the corresponding destination. This problem is now solved. In addition to the information published in the topic page, you can always find a full description of destinations:

* destination 1: Achieving global leadership in climate-neutral, circular and digitised industrial and digital value chains;

* destination 2: Achieving technological leadership for Europe's open strategic autonomy in raw materials, chemicals and innovative materials;

* destination 4: Achieving open strategic autonomy in digital and emerging enabling technologies;

* destination 6: Digital and industrial technologies driving human-centric innovation,

that are relevant for the call in the Work Programme 2025 part for “Industry”. Please select from the work programme the destination relevant to your topic and take into account the description and expected impacts of that destination for the preparation of your proposal.

Last Changed: May 22, 2025
The submission session is now available for: HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-64, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-37, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-66, HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-31, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-44, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-64, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-63, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-34, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-32, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-38, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-63, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-36, HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-31, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-05, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-39, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-01, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-62, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-45, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-33, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-60, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-62
Physical and cognitive augmentation in advanced manufacturing (Made in Europe Partnership) (RIA) | Grantalist