Accelerate the uptake of life-cycle assessment (LCA) for Safe and Sustainable by Design (SSbD) chemicals and materials and resulting products (RIA)
HORIZON Research and Innovation Actions
Basic Information
- Identifier
- HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52
- Programme
- INDUSTRY
- Programme Period
- 2021 - 2027
- Status
- Closed (31094503)
- Opening Date
- May 22, 2025
- Deadline
- September 23, 2025
- Deadline Model
- single-stage
- Budget
- €15,000,000
- Min Grant Amount
- €4,000,000
- Max Grant Amount
- €5,000,000
- Expected Number of Grants
- 3
- Keywords
- HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52HORIZON-CL4-2025-01
Description
Projects are expected to contribute to the following outcomes:
- Support the implementation of EU strategies such as the proposed Eco-design for Sustainable Products Regulation (ESPR)[1], the EU Ecolabel[2], the Green Claims Directive proposal[3], the One-Substance-One-Assessment package[4], the Batteries Regulation[5], the Critical Raw Materials Act[6] and the Net Zero Industry Act[7] with scientific evidence on sustainability throughout the entire life cycle of chemicals and materials,;
- Reduce significantly the cost to apply LCA at company level, including for SMEs, compared to current costs;
- Allow an efficient and simplified LCA application at early stage of design and facilitate decision making for companies and policy makers by providing user-friendly and cost-effective tools, methods and data;
- Provide advanced, reliable and predictive life cycle models and impact assessment methods, allowing for a satisfactory measurement of planetary boundaries;
Proposals should identify and fill the gaps in LCA tools, methods and data used for improving the environmental sustainability and efficiency of chemicals, materials and resulting products, taking also into account the criticality of raw materials. The Environmental Footprint (EF) methods should in particular be built on. All stages from raw material extraction to end-of-life disposal of products should be included. Data-driven decisions and actions for a greener and more sustainable future should be enabled, while respecting planetary boundaries. The tools should be in compliance with the Safe and Sustainable by Design[8] framework, hence to be considered as a reference in the proposal.
Multidisciplinary research activities should address all the following:
- Develop advanced, user-friendly LCA tools and methodologies that allow for a comprehensive assessment of the environmental sustainability of the entire lifecycle of chemicals, materials and resulting products whilst considering planetary boundaries;
- Develop LCA datasets, in particular building on the EC PEF methods, from design to end-of-life of at least three relevant chemicals or materials and a selection of their resulting products. The selected substances should be emerging alternatives to substances of concern (as defined in the ESPR proposal) and should have a high socio-economic value;
- Develop solutions to fill in the identified data and assessment gaps and to estimate LCA uncertainty, using advanced digital technologies, modelling, machine learning and artificial intelligence;
- Feed relevant sustainability databases managed by the European Institutions and Agencies, such as the European Platform on LCA[9] (EPLCA), with FAIR[10] data and ensure new tools developed are findable by stakeholders.
- Provide guidance for LCA modelling of circularity scenarios for chemicals, materials and resulting products, in alignment with EC PEF methods and the SSbD framework;
- Ensure that the developed tools, methods and datasets are cost-effective and user-friendly in order to increase uptake and use in industry;
- Develop guidelines and user-friendly solutions to enable a seamless integration of the new LCA approaches with existing safety assessment tools and methods (notably the EC PEF method) to ensure a holistic SSbD assessment from the early innovation phases;
- Engage with the wider stakeholder community, especially with SMEs, to promote a harmonised use of the proposed tools and methodologies;
- Perform training and knowledge transfer activities to promote LCA and SSbD knowledge as well as life cycle thinking within the R&I ecosystem;
- Projects should contribute to yearly policy briefs and technical discussions, for example under the Eco-design for Sustainable Products Regulation (ESPR)[1] or with the EF Technical Advisory Board;
- Proposals should leverage the experience of Social Sciences and Humanities (SSH) researchers in refining models related to child labour, employment conditions, and other socio-economic factors within LCA;
- The improved/advanced tools and methods should consider evaluating the economic and social dimension of sustainability at product level based on a functional unit.
Proposals should indicate to which chapters of the Strategic Research and Innovation Plan for chemicals and materials[12] they will contribute.
International collaboration is encouraged.
Projects should build on, or seek collaboration with, existing projects and develop synergies with other relevant European, national or regional initiatives, funding programmes and platforms. Specifically, projects should collaborate with the Partnership on Assessment of Risks from Chemicals[13] (PARC) and ensure complementarity with the SSbD toolbox[14] and also engage with the IRISS project[15] on the different value chains. Additionally, projects are encouraged to build on the results obtained by the ORIENTING[16] project funded under the CE-NMBP-42-2020[17] topic which has aimed to operationalise methodologies for LCA and to propose options to further advance the Product Environmental Footprint (PEF). Proposals should allocate the necessary resources for the above activities. Where relevant, proposers are encouraged to take advantage of and connecting to European research infrastructures and services.
Synergies with Horizon Europe missions as relevant are encouraged.
[1] Proposal for Ecodesign for Sustainable Products Regulation
[2] EU Ecolabel
[3] Green Claims Directive proposal
[4] ‘One substance, one assessment' chemicals assessment reform
[6] European Critical Raw Materials Act
[8] See documents defining the SSbD framework on: https://ec.europa.eu/info/research-and-innovation/research-area/industrial-research-and-innovation/key-enabling-technologies/advanced-materials-and-chemicals_en
[9] European Platform on LCA | EPLCA
[10] Findable, Accessible, Interoperable, Reusable
[11] Proposal for Ecodesign for Sustainable Products Regulation
[13] Partnership for the Assessment of Risks from Chemicals | Parc
[14] Safe and sustainable by design toolbox | Parc
[15] About IRISS
[16] Orienting EU Project
Destination & Scope
The research and innovation under this Destination will contribute to a paradigm shift, as regards the availability, development, use and disposal of chemicals and materials. This is necessary to guarantee Europe’s technological sovereignty and capacity to deliver on the twin green and digital transitions (it is thus strongly linked to the objectives of the Destination ‘Achieving global leadership in climate-neutral, circular and digitised industrial and digital value chains’).
To enable such a shift, an innovative, strong European R&I ecosystem for circular chemicals and materials is needed, working across different technology readiness levels. Bringing knowledge and skills together across the materials’ value chains is key to ensuring that this shift can materialise.
The requirements of the European Green Deal for safety, sustainability and circularity should be considered across the life cycle of a chemical or material. The 2022 Commission Recommendation on ‘Safe and Sustainable by Design’ (SSbD) sets out a new framework on how to achieve these objectives.
R&I activities should contribute to strengthen EU’s critical raw materials capacities along all stages of the value chain, increasing our resilience by reducing dependencies, increasing preparedness and promoting supply chain sustainability and circularity, in line with the Critical Raw Materials Act. It is necessary to improve the energy and process efficiency of extractive and processing activities and minimise their environmental impact, including GHG emissions. Advancements need to be made on finding options for replacing critical raw materials with other (advanced) materials offering at least the same functionality and taking into account the existing environmental concerns.
Advanced materials (including amongst others nano- and 2D materials) and chemicals are designed with functionality in mind. Compared to conventional materials, they have novel properties that significantly step-up performance. New digital tools are needed such as common data spaces, digital twins, industrial virtual worlds, as well as novel (autonomous) design, synthesis, development, characterisation and fabrication tools as well as continuous training of scientists on these new tools.
To secure unimpeded market entry, appropriate test methods are needed. New chemicals and materials should be developed using the SSbD framework and with the efficiency and circularity of materials in mind, also for their inclusion in products. This calls for tools, models and data for robust SSbD, including animal-free new approach methodologies and systematic life-cycle assessments. Bio-based advanced materials/chemicals and the integration and interaction of biological and artificial materials and components offer new opportunities to reduce resource dependencies and maintain sustainability.
Achieving the circularity of both raw materials and advanced materials is a key future challenge. Establishing new material flows, recovery, recycling and upcycling of materials from waste are challenges in themselves, but they also require information sharing along and across value chains and development of new business models allowing to foster innovative solutions related to technological progress, such as in materials design.
Uptake of advanced materials as well as a more efficient use of materials should be fostered in product and materials-based technology developments. This also requires new business models to be developed for the deployment of circular technologies and value chains as well as for providing product-as-a-service models, on-demand manufacturing, take-back-schemes and other service-based businesses. Strong support to SMEs is required so they can thrive in this materials ecosystem.
Business cases and exploitation strategies for industrialisation:
This section applies only to those topics in this Destination, for which proposals should demonstrate the expected outcomes by including a business case and exploitation strategy for industrialisation.
A business case and a credible initial exploitation strategy are essential components in the ultimate success of an industry-based project, as well as its prospects to attract further investments for deployment. They will both be decisive factors under the impact criterion, and proposers are encouraged to use the extended page limit to present a carefully considered business case and exploitation strategy, backed by the management of the companies involved.
The business case should demonstrate the expected impact of the proposal in terms of enhanced market opportunities for the participants and deployment in the EU, in the short to medium term. It should describe the targeted market(s); estimated market size in the EU and globally; user and customer needs; and demonstrate that the solutions will match the market and user needs in a cost-effective manner; and describe the expected market position and competitive advantage.
The exploitation strategy should identify obstacles, requirements and necessary actions involved in reaching higher TRLs (Technology Readiness Levels), for example: securing the required investments, including through possible synergies with other programmes; accessing the required skills; matching value chains; enhancing product robustness; securing industrial integrators; and user acceptance.
For TRLs 6 and 7, a credible strategy to achieve future full-scale deployment in the EU is expected, indicating the intentions of the industrial partners after the end of the project.
Where relevant, in the context of skills, it is recommended to develop training material to endow workers with the right skillset in order to support the uptake and deployment of new innovative products, services, and processes developed in the different projects. This material should be tested and be scalable, and can potentially be up-scaled through the European Social Fund Plus (ESF+). This will help the European labour force to close the skill gaps in the relevant sectors and occupational groups and improve employment and social levels across the EU and associated countries.
For topics in this destination, consortia (if selected for funding) could consider voluntary contributions in terms of data, indicators and knowledge to relevant Joint Research Centre (JRC) platforms for capitalising the knowledge developed in their projects and become more policy relevant:
- INnovation Centre for Industrial Transformation and Emissions (INCITE) (https://innovation-centre-for-industrial-transformation.ec.europa.eu/).
- The Energy and Industry Geography Lab: EIGL (https://energy-industry-geolab.jrc.ec.europa.eu/).
Innovation Actions — Legal entities established in China are not eligible to participate in Innovation Actions in any capacity. Please refer to the Annex B of the General Annexes of this Work Programme for further details.
Eligibility & Conditions
General conditions
1. Admissibility Conditions: Proposal page limit and layout
2. Eligible Countries
described in Annex B of the Work Programme General Annexes.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.
3. Other Eligible Conditions
described in Annex B of the Work Programme General Annexes.
4. Financial and operational capacity and exclusion
described in Annex C of the Work Programme General Annexes.
5a. Evaluation and award: Award criteria, scoring and thresholds
are described in Annex D of the Work Programme General Annexes.
5b. Evaluation and award: Submission and evaluation processes
are described in Annex F of the Work Programme General Annexes and the Online Manual.
5c. Evaluation and award: Indicative timeline for evaluation and grant agreement
described in Annex F of the Work Programme General Annexes.
6. Legal and financial set-up of the grants
Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025). [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf]].
described in Annex G of the Work Programme General Annexes.
Specific conditions
described in the [specific topic of the Work Programme]
Application and evaluation forms and model grant agreement (MGA):
Application form templates — the application form specific to this call is available in the Submission System
Standard application form (HE RIA, IA)
Evaluation form templates — will be used with the necessary adaptations
Standard evaluation form (HE RIA, IA)
Guidance
Model Grant Agreements (MGA)
Call-specific instructions
Information on financial support to third parties (HE)
Additional documents:
HE Main Work Programme 2025 – 1. General Introduction
HE Main Work Programme 2025 – 7. Digital, Industry and Space
HE Main Work Programme 2025 – 14. General Annexes
HE Framework Programme 2021/695
HE Specific Programme Decision 2021/764
EU Financial Regulation 2024/2509
Decision authorising the use of lump sum contributions under the Horizon Europe Programme
Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment
EU Grants AGA — Annotated Model Grant Agreement
Funding & Tenders Portal Online Manual
Support & Resources
Online Manual is your guide on the procedures from proposal submission to managing your grant.
Horizon Europe Programme Guide contains the detailed guidance to the structure, budget and political priorities of Horizon Europe.
Funding & Tenders Portal FAQ – find the answers to most frequently asked questions on submission of proposals, evaluation and grant management.
Research Enquiry Service – ask questions about any aspect of European research in general and the EU Research Framework Programmes in particular.
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CEN-CENELEC Research Helpdesk and ETSI Research Helpdesk – the European Standards Organisations advise you how to tackle standardisation in your project proposal.
The European Charter for Researchers and the Code of Conduct for their recruitment – consult the general principles and requirements specifying the roles, responsibilities and entitlements of researchers, employers and funders of researchers.
Partner Search help you find a partner organisation for your proposal.
Latest Updates
CALL UPDATE: PROPOSAL NUMBERS
Call HORIZON-CL4-2025-01 has closed on the 23/09/2025.
639 proposals have been submitted.
The breakdown per topic is:
Topic ID | Topic title | Action type | Proposals submitted |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-01 | Integrated approaches for remanufacturing (Made in Europe Partnership) (IA) | IA | 80 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02 | Physical and cognitive augmentation in advanced manufacturing (Made in Europe Partnership) (RIA) | RIA | 94 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-05 | Advanced manufacturing technologies for leadership of EU manufacturers in products for the net-zero industry (Made in Europe Partnership) (IA) | IA | 64 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-31 | From heat-driven processes to the use of mechanical and electric forces (Processes4Planet Partnership) (IA) | IA | 13 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-32 | Green and resilient flexible production processes (Processes4Planet Partnership) (IA) | IA | 19 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-33 | Integrated use of renewable energy carriers in industrial sites (Processes4Planet Partnership) (RIA) | RIA | 35 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-34 | Smart integration of net zero technologies into Energy Intensive industries (Processes4Planet and Made in Europe Partnerships) (IA) | IA | 12 |
TWIN-TRANSITION-36 | Safe and clean processing technologies and products (Processes4Planet Partnership) (RIA) | RIA | 25 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-37 | Solving issues in carbon-neutral iron and steel making processes with diverse input materials of varying quality (Clean Steel Partnership) (RIA) | RIA | 22 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-38 | Synergies and mutual learning with national and regional initiatives in Europe on Industrial decarbonisation (Processes4Planet and Clean Steel Partnerships) (CSA) | CSA | 1 |
HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-39 | Towards human-centric, sustainable and resilient energy-intensive industries (Processes4Planet and Clean Steel Partnerships) (CSA) | CSA | 3 |
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-31 | Digitally enabled local-for-local textile and apparel production (Textiles for the Future Partnership) (IA) | IA | 33 |
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-44 | Innovative Advanced Materials Innovation Procurement (CSA) | CSA | 4 |
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-45 | Materials Commons for Europe (IA) | IA | 3 |
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52 | Accelerate the uptake of life-cycle assessment (LCA) for Safe and Sustainable by Design (SSbD) chemicals and materials and resulting products (RIA) | RIA | 35 |
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-61 | Technologies for critical raw materials and strategic raw materials from end-of-life products (IA) | IA | 38 |
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-62 | Strategic Partnerships for Raw Materials: Innovative approaches for sustainable production of Critical Raw Materials (IA) | IA | 31 |
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-63 | Innovative solutions for the sustainable production for semiconductor raw materials (IA) | IA | 7 |
HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-64 | EU Co-funded Partnership on raw materials for the green and digital transition (Programme Co-fund action) | COFUND | 1 |
HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61 | AI Foundation models in science (GenAI4EU) (RIA) | RIA | 47 |
HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62 | Facilitated cooperation for AI in Science (CSA) | CSA | 7 |
HORIZON-CL4-INDUSTRY-2025-01-HUMAN-60 | Horizon Standardisation Booster (CSA) | CSA | 3 |
HORIZON-CL4-INDUSTRY-2025-01-HUMAN-61 | Standardisation landscape analyses tool (CSA) | CSA | 3 |
HORIZON-CL4-INDUSTRY-2025-01-HUMAN-62 | Artificial Intelligence for knowledge valorisation (CSA) | CSA | 15 |
HORIZON-CL4-INDUSTRY-2025-01-HUMAN-63 | Value creation pilots for scaling up innovative solutions (CSA) | CSA | 10 |
HORIZON-CL4-INDUSTRY-2025-01-HUMAN-64 | Pilot initiatives on Technology Infrastructures (CSA) | CSA | 20 |
HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65 | Network of Industry 5.0 system innovation hubs in connected Regional Innovation Valleys (IA) | IA | 8 |
HORIZON-CL4-INDUSTRY-2025-01-HUMAN-66 | Assessment of Technology Infrastructure needs in Ukraine (CSA) | CSA | 6 |
Total: | 639 | ||
Evaluation results are expected to be communicated around mid-January 2026.
A.R.
Reminder on proposal part B page limit and formatting conditions
1. Proposal part B page limit
The title, list of participants and sections 1, 2 and 3, together, should not be longer than page limit, indicated in a proposal part B template inside the Submission System. All tables, figures, references and any other element pertaining to these sections must be included as an integral part of these sections and are thus counted against this page limit.
The page limit will be applied automatically. At the end of a proposal part B template inside the Submission System you can see the structure of the actual proposal that you need to submit, please remove all instruction pages that are watermarked.
If you attempt to upload a proposal longer than the specified limit before the deadline, you will receive an automatic warning and will be advised to shorten and re-upload the proposal. After the deadline, excess pages (in over-long proposals/applications) will be automatically made invisible, and will not be taken into consideration by the experts. The proposal is a self-contained document. Experts will be instructed to ignore hyperlinks to information that is specifically designed to expand the proposal, thus circumventing the page limit.
Please, do not consider the page limit as a target! It is in your interest to keep your text as concise as possible, since experts rarely view unnecessarily long proposals in a positive light.
2.Proposal part B formatting conditions
The following formatting conditions apply (as listed in a proposal part B template inside the Submission System) and will be checked by the Agency during an admissibility check of submitted proposals.
The reference font for the body text of proposals is Times New Roman (Windows platforms), Times/Times New Roman (Apple platforms) or Nimbus Roman No. 9 L (Linux distributions).
The use of a different font for the body text is not advised and is subject to the cumulative conditions that the font is legible and that its use does not significantly shorten the representation of the proposal in number of pages compared to using the reference font (for example with a view to bypass the page limit).
The minimum font size allowed is 11 points. Standard character spacing and a minimum of single line spacing is to be used. This applies to the body text, including text in tables.
Text elements other than the body text, such as headers, foot/end notes, captions, formula's, may deviate, but must be legible.
The page size is A4, and all margins (top, bottom, left, right) should be at least 15 mm (not including any footers or headers).
Proposal part B template inside the Submission System document is tagged. Do not delete the tags; they are needed for our internal processing of information, mostly for statistical gathering. In that light, please do not move, delete, re-order, alter tags in any way, as they might create problems in our internal processing tools. Tags do not affect or influence the outcome of your application.
Please note that due to a technical issue, during the first days of publication of this call, the topic page did not display the description of the corresponding destination. This problem is now solved. In addition to the information published in the topic page, you can always find a full description of destinations:
* destination 1: Achieving global leadership in climate-neutral, circular and digitised industrial and digital value chains;
* destination 2: Achieving technological leadership for Europe's open strategic autonomy in raw materials, chemicals and innovative materials;
* destination 4: Achieving open strategic autonomy in digital and emerging enabling technologies;
* destination 6: Digital and industrial technologies driving human-centric innovation,
that are relevant for the call in the Work Programme 2025 part for “Industry”. Please select from the work programme the destination relevant to your topic and take into account the description and expected impacts of that destination for the preparation of your proposal.