Closed

Facilitated cooperation for AI in Science (CSA)

HORIZON Coordination and Support Actions

Basic Information

Identifier
HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62
Programme
INDUSTRY
Programme Period
2021 - 2027
Status
Closed (31094503)
Opening Date
May 22, 2025
Deadline
September 23, 2025
Deadline Model
single-stage
Budget
€15,000,000
Min Grant Amount
€4,000,000
Max Grant Amount
€5,000,000
Expected Number of Grants
3
Keywords
HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62HORIZON-CL4-2025-01

Description

Expected Outcome:

Projects are expected to contribute to the following outcomes:

  • Identify the long-term research challenges where AI can make a meaningful breakthrough contributing to EU’s competitive edge in selected scientific disciplines/areas, through a Strategic Research and Innovation Agenda.
  • Provide evidence to structure the resources for AI in Science at European level, as a feasibility test towards potential R&I initiatives beyond the CSA that could optimise access to relevant data, infrastructure and talent across different scientific domains for more and better AI-enabled research.
  • Coordinate, strengthen the network and raise awareness and a community of scientists, including citizen scientists, research organisations and stakeholders towards new paradigms of research with AI.
Scope:

Artificial intelligence is a game-changer for science and innovation, and promises significant opportunities to boost the European competitive edge in R&I that need to be capitalised on. The aim of the CSA is to structure AI-enabled research in Europe and assess options towards optimising the ecosystem for AI in Science in Europe, through a Strategic Research & Innovation Agenda and assessing the potential for possible future R&I initiative(s), in line with the recommendations of the Scientific Advice Mechanism[1], and the European Commission President’s political guidelines, for the setting up of an AI Research Council[2]..

The project should develop a Strategic Research and Innovation Agenda for AI in Science by mobilising large groups of domain and AI researchers in different fields to identify key long-term research challenges in a diverse range of scientific areas where AI can make a meaningful difference for scientific breakthroughs, which are compelling to the EU competitive, environmental and social policy agenda. The project should come up with pilot areas from across Horizon Europe Pillar II Clusters, building on Europe’s competitive advantages in science and AI technologies. The research challenges should be related to prediction and design problems in the different scientific fields identified that could be solved with AI.

The SRIA should also include areas where AI can improve generic scientific tasks e.g virtual research assistant / tools for literature-based discovery, for improving / enabling research workflows, lab automation and collaborative human-AI work in science. Research priority areas involving the use of models based on frugal AI, which are more compact, more efficient and less energy intensive, as well as human-centric and trustworthy AI for scientific work should also be explored.

The project should build evidence and assess the needs and potential for R&I initiatives for AI in Science beyond the CSA, in an effort to identify ways to improve the EU landscape for support for AI in Science, to be discussed and agreed upon with the Commission and the Member States. The assessment should identify the ways for improving data access, infrastructure and support services, as well as skills and talent-related needs to boost the integration of AI in different fields of science at larger scale in Europe in research processes and lab automation, while promoting reproducibility, transparency and open science. It should also identify options for EU to better enable cooperative development and sharing of AI models for scientific discovery across different scientific fields. It should also take into account existing EU efforts to support access to data, research infrastructures, networks, HPC.

Different scenarios of R&I initiatives and infrastructure improvements should be prototyped together with a diverse range of users and stakeholders from the research community, industry, start-ups, civil society and policy-maker communities. Based on the feasibility test results, the project should develop a roadmap on the needed steps for a more effective coordination between the domain and AI scientific communities in Europe and the needed upgrades in service and infrastructure provision at EU level for the integration of AI in different scientific fields, including research processes engaging citizens and civil society, e.g. Citizen Science.

The proposals should also provide coordination and dissemination for interdisciplinary AI-enabled science to facilitate stakeholder engagement, coordination and promotion of AI in Science initiatives across Europe. The CSA should develop a website, organise awareness raising events for the benefits of AI in Science and create opportunities for exchanging on good practices.

Projects should build on or seek collaboration with existing projects and develop synergies with other relevant European, national or regional initiatives, funding programmes and platforms, in particular with EU-level initiatives such as EOSC[3],EuroHPC Joint Untedtaking[4], ESFRI,[5]AI Factories,[6] the EU AI, Data and Robotics Partnership,[7]AI4EOSC[8] the AI on Demand Platform[9] and the GenAI4EU Central Hub.

[1] See European Commission’s Group of Chief Scientific Advisors (2024). Successful and timely uptake of artificial intelligence in science in the EU: scientific opinion. Brussels: European Commission.

[2] See Ursula von der Leyen, Political Guidelines For The Next European Commission 2024−2029

[3] Home | European Open Science Cloud - EU Node and the selected projects from the HORIZON-INFRA-2025-01-EOSC-04: Advancing AI-readiness and Machine-Actionability in the EOSC Ecosystem.

[4] Homepage - EuroHPC JU

[5] www.esfri.eu

[6] AI Factories | Shaping Europe’s digital future

[7] Adra Association

[8] AI4EOSC - AI4EOSC

[9] AI-On-Demand Portal - AIoD - AI on Demand

Destination & Scope

Destination 4 ensures Europe’s strategic autonomy while preserving an open economy in those technologies that will be key for a deep digital transformation of industry, public services and society, while fully playing its enabling role in the twin transition. As set out in the European Chips Act, the top-priorities are to i) strengthen processes undertaken at critical stages in the semiconductor and quantum chips value chain, including chip design and manufacturing technologies, and ii) address the use of new materials and green technologies, energy efficiency and the integration of circularity and life-cycle assessment.

Destination 4 will address high value-added hardware needs for core, cloud and edge, fast-sensing, low-latency and high-bandwidth data transmission, and help secure the supply of critical components for key markets, such as automotive, health, automation and mobility systems. For this purpose, significant human capacity will be required in chip manufacturing to ensure: (i) the strengthening of processes undertaken at critical stages in the value chain; and (ii) that workers can take up quality jobs created as part of these priorities, including through the activities undertaken by the joint undertaking initiative.

In addition, future needs in microelectronics (such as performance, size, cost, energy efficiency, environmental impact, new materials, concepts, architectures, integration) may also be addressed to make sure Europe’s microelectronics industry remains competitive. Opportunities may come from non-volatile memories, spintronics, in-memory computing, neuromorphic and other emerging technologies. Photonics research will lead to fast and versatile sensing and imaging, and energy-efficient building blocks for networks and data centres. The cluster will also push for chip-level integration of photonics and optoelectronics.

The cloud/edge/internet of things will be transformed into an agile and situation-aware infrastructure that brings data to where and when it is needed. Within these smart digital infrastructures, end-to-end artificial intelligence, from the core to the edge and across all technology layers, will be key for on-demand supply of optimal data-, communication-, and computing resource orchestration, with optimal use of energy while preserving privacy and ensuring resilience. European sovereignty in the cloud-edge server market will be strengthened through the power of open-source software, complementing the RISC-V based European Processor Initiative that aims to increase Europe’s independence in high performance computing hardware.

Cluster 4 will transform the user experience. It will push the frontiers of virtual and extended realities (VR/XR) and of open, human-centric virtual worlds for industry, entertainment and arts, public services and people alike, e.g. by leveraging social innovation. It envisages a vibrant R&I ecosystem that strategically joins-up research and development on sophisticated VR/XR optics and displays, multimodal human-computer interaction, authoring tools, real-time spatial computing, rendering, integration and application research. Improved sensing, fast processing and low-latency will be challenging for the underlying cloud/edge/Internet of things. Along similar lines, the way in which the virtual world meets the physical world will continue to evolve, thanks to all kinds of robots and other smart devices that involve self- and context awareness, spatial intelligence, exploiting the best in bias-free AI, engineering and design for game-changing physical characteristics, functional or cognitive capabilities, acute perception, autonomy and safe interaction.

Artificial intelligence underpins many of these changes and Cluster 4 will strengthen and consolidate R&I in this area. For example, today’s generative models are a preview of how virtual worlds and multimodal user-experiences could be produced on-demand. Research on core learning and analysis techniques (incremental, frugal and collaborative), as well as next generation smart robotic systems, will keep Europe at the cutting edge of AI. Artificial Intelligence is also key to keep the competitiveness and strategic autonomy of the EU scientific sector. The EU's comprehensive approach to achieving leadership in AI is reflected in its Apply AI Strategy, which aims at establishing Europe as a global leader in the development and adoption of AI. By fostering a vibrant AI ecosystem, the EU seeks to make Europe a hub for AI innovation and growth, where world-class AI models are developed and integrated into strategic sectors. This initiative is designed to drive innovation, economic growth, and competitiveness, while ensuring that the benefits of AI are shared by all. The topics related to Generative AI included in this destination will support the implementation of the GenAI4EU initiative included in the AI Innovation Package of 24 January 2024. They constitute, moreover, an integral part of the broader Apply AI strategy. By aligning these efforts with the GenAI4EU initiative and the Apply AI strategy, the EU aims to create a cohesive and coordinated approach to AI development and adoption, one that promotes European excellence and leadership in this critical field.

Europe’s long-term competitiveness in the digital area requires continuous scouting and early, low-TRL cross-disciplinary work on new and emerging technologies, dissociated from the main roadmaps. This would encourage collaboration in research and cross-fertilisation between disciplines and sectors on new approaches in: (i) microelectronics; (ii) power electronics; (iii) photonics and photon/phonon/spin/electron integration; (iv) unconventional, hybrid, neuromorphic, nature-inspired or bio-intelligent paradigms; and (v) novel systems and infrastructure architectures.

Europe’s strength in quantum technologies (including in quantum communications and optical satellite communications, etc.) is a strategic asset for its future security and independence. Cluster 4 supports early and mature quantum technologies and stimulates their industrial uptake, e.g. through experimentation and testing environments for integrating them into standard industrial design and manufacturing. Equally transformative, two-dimensional materials (2DM) could positively affect many industries, including ICT. While further exploring the vast range of 2DMs, Cluster 4 will also work towards completing a fully European supply chain and scaling up the development and piloting of 2DM technologies and devices for more industrial fields.

Eligibility & Conditions

General conditions

1. Admissibility Conditions: Proposal page limit and layout

described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.

Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.

2. Eligible Countries

described in Annex B of the Work Programme General Annexes.

A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.

3. Other Eligible Conditions

described in Annex B of the Work Programme General Annexes.

4. Financial and operational capacity and exclusion

described in Annex C of the Work Programme General Annexes.

5a. Evaluation and award: Award criteria, scoring and thresholds

are described in Annex D of the Work Programme General Annexes.

5b. Evaluation and award: Submission and evaluation processes

are described in Annex F of the Work Programme General Annexes and the Online Manual.

5c. Evaluation and award: Indicative timeline for evaluation and grant agreement

described in Annex F of the Work Programme General Annexes.

6. Legal and financial set-up of the grants

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025). [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf]].

described in Annex G of the Work Programme General Annexes.

Specific conditions

described in the [specific topic of the Work Programme]

Support & Resources

Online Manual is your guide on the procedures from proposal submission to managing your grant.

Horizon Europe Programme Guide contains the detailed guidance to the structure, budget and political priorities of Horizon Europe.

Funding & Tenders Portal FAQ – find the answers to most frequently asked questions on submission of proposals, evaluation and grant management.

Research Enquiry Service – ask questions about any aspect of European research in general and the EU Research Framework Programmes in particular.

National Contact Points (NCPs) – get guidance, practical information and assistance on participation in Horizon Europe. There are also NCPs in many non-EU and non-associated countries (‘third-countries’).

Enterprise Europe Network – contact your EEN national contact for advice to businesses with special focus on SMEs. The support includes guidance on the EU research funding.

IT Helpdesk – contact the Funding & Tenders Portal IT helpdesk for questions such as forgotten passwords, access rights and roles, technical aspects of submission of proposals, etc.

European IPR Helpdesk assists you on intellectual property issues.

CEN-CENELEC Research Helpdesk and ETSI Research Helpdesk – the European Standards Organisations advise you how to tackle standardisation in your project proposal.

The European Charter for Researchers and the Code of Conduct for their recruitment – consult the general principles and requirements specifying the roles, responsibilities and entitlements of researchers, employers and funders of researchers.

Partner Search help you find a partner organisation for your proposal.

Latest Updates

Last Changed: September 23, 2025

CALL UPDATE: PROPOSAL NUMBERS



Call HORIZON-CL4-2025-01 has closed on the 23/09/2025.

639 proposals have been submitted.



The breakdown per topic is:

Topic ID

Topic title

Action type

Proposals submitted

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-01

Integrated approaches for remanufacturing (Made in Europe Partnership) (IA)

IA

80

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02

Physical and cognitive augmentation in advanced manufacturing (Made in Europe Partnership) (RIA)

RIA

94

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-05

Advanced manufacturing technologies for leadership of EU manufacturers in products for the net-zero industry (Made in Europe Partnership) (IA)

IA

64

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-31

From heat-driven processes to the use of mechanical and electric forces (Processes4Planet Partnership) (IA)

IA

13

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-32

Green and resilient flexible production processes (Processes4Planet Partnership) (IA)

IA

19

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-33

Integrated use of renewable energy carriers in industrial sites (Processes4Planet Partnership) (RIA)

RIA

35

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-34

Smart integration of net zero technologies into Energy Intensive industries (Processes4Planet and Made in Europe Partnerships) (IA)

IA

12

TWIN-TRANSITION-36

Safe and clean processing technologies and products (Processes4Planet Partnership) (RIA)

RIA

25

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-37

Solving issues in carbon-neutral iron and steel making processes with diverse input materials of varying quality (Clean Steel Partnership) (RIA)

RIA

22

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-38

Synergies and mutual learning with national and regional initiatives in Europe on Industrial decarbonisation (Processes4Planet and Clean Steel Partnerships) (CSA)

CSA

1

HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-39

Towards human-centric, sustainable and resilient energy-intensive industries (Processes4Planet and Clean Steel Partnerships) (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-31

Digitally enabled local-for-local textile and apparel production (Textiles for the Future Partnership) (IA)

IA

33

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-44

Innovative Advanced Materials Innovation Procurement (CSA)

CSA

4

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-45

Materials Commons for Europe (IA)

IA

3

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52

Accelerate the uptake of life-cycle assessment (LCA) for Safe and Sustainable by Design (SSbD) chemicals and materials and resulting products (RIA)

RIA

35

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-61

Technologies for critical raw materials and strategic raw materials from end-of-life products (IA)

IA

38

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-62

Strategic Partnerships for Raw Materials: Innovative approaches for sustainable production of Critical Raw Materials (IA)

IA

31

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-63

Innovative solutions for the sustainable production for semiconductor raw materials (IA)

IA

7

HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-64

EU Co-funded Partnership on raw materials for the green and digital transition (Programme Co-fund action)

COFUND

1

HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61

AI Foundation models in science (GenAI4EU) (RIA)

RIA

47

HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62

Facilitated cooperation for AI in Science (CSA)

CSA

7

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-60

Horizon Standardisation Booster (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-61

Standardisation landscape analyses tool (CSA)

CSA

3

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-62

Artificial Intelligence for knowledge valorisation (CSA)

CSA

15

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-63

Value creation pilots for scaling up innovative solutions (CSA)

CSA

10

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-64

Pilot initiatives on Technology Infrastructures (CSA)

CSA

20

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65

Network of Industry 5.0 system innovation hubs in connected Regional Innovation Valleys (IA)

IA

8

HORIZON-CL4-INDUSTRY-2025-01-HUMAN-66

Assessment of Technology Infrastructure needs in Ukraine (CSA)

CSA

6

Total:

639



Evaluation results are expected to be communicated around mid-January 2026.



A.R.



Last Changed: September 15, 2025

Reminder on proposal part B page limit and formatting conditions



1.    Proposal part B page limit



The title, list of participants and sections 1, 2 and 3, together, should not be longer than page limit, indicated in a proposal part B template inside the Submission System. All tables, figures, references and any other element pertaining to these sections must be included as an integral part of these sections and are thus counted against this page limit.



The page limit will be applied automatically. At the end of a proposal part B template inside the Submission System you can see the structure of the actual proposal that you need to submit, please remove all instruction pages that are watermarked.



If you attempt to upload a proposal longer than the specified limit before the deadline, you will receive an automatic warning and will be advised to shorten and re-upload the proposal. After the deadline, excess pages (in over-long proposals/applications) will be automatically made invisible, and will not be taken into consideration by the experts. The proposal is a self-contained document. Experts will be instructed to ignore hyperlinks to information that is specifically designed to expand the proposal, thus circumventing the page limit.



Please, do not consider the page limit as a target! It is in your interest to keep your text as concise as possible, since experts rarely view unnecessarily long proposals in a positive light.



2.Proposal part B formatting conditions



The following formatting conditions apply (as listed in a proposal part B template inside the Submission System) and will be checked by the Agency during an admissibility check of submitted proposals.



The reference font for the body text of proposals is Times New Roman (Windows platforms), Times/Times New Roman (Apple platforms) or Nimbus Roman No. 9 L (Linux distributions).

The use of a different font for the body text is not advised and is subject to the cumulative conditions that the font is legible and that its use does not significantly shorten the representation of the proposal in number of pages compared to using the reference font (for example with a view to bypass the page limit).



The minimum font size allowed is 11 points. Standard character spacing and a minimum of single line spacing is to be used. This applies to the body text, including text in tables.



Text elements other than the body text, such as headers, foot/end notes, captions, formula's, may deviate, but must be legible.



The page size is A4, and all margins (top, bottom, left, right) should be at least 15 mm (not including any footers or headers).



Proposal part B template inside the Submission System document is tagged. Do not delete the tags; they are needed for our internal processing of information, mostly for statistical gathering. In that light, please do not move, delete, re-order, alter tags in any way, as they might create problems in our internal processing tools. Tags do not affect or influence the outcome of your application.



Last Changed: June 10, 2025

Please note that due to a technical issue, during the first days of publication of this call, the topic page did not display the description of the corresponding destination. This problem is now solved. In addition to the information published in the topic page, you can always find a full description of destinations:

* destination 1: Achieving global leadership in climate-neutral, circular and digitised industrial and digital value chains;

* destination 2: Achieving technological leadership for Europe's open strategic autonomy in raw materials, chemicals and innovative materials;

* destination 4: Achieving open strategic autonomy in digital and emerging enabling technologies;

* destination 6: Digital and industrial technologies driving human-centric innovation,

that are relevant for the call in the Work Programme 2025 part for “Industry”. Please select from the work programme the destination relevant to your topic and take into account the description and expected impacts of that destination for the preparation of your proposal.

Last Changed: May 22, 2025
The submission session is now available for: HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-52, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-64, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-37, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-65, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-66, HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-31, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-02, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-44, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-64, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-63, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-34, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-32, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-38, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-63, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-36, HORIZON-CL4-INDUSTRY-2025-01-DIGITAL-62, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-31, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-05, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-61, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-39, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-01, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-62, HORIZON-CL4-INDUSTRY-2025-01-MATERIALS-45, HORIZON-CL4-INDUSTRY-2025-01-TWIN-TRANSITION-33, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-60, HORIZON-CL4-INDUSTRY-2025-01-HUMAN-62
Facilitated cooperation for AI in Science (CSA) | Grantalist