Challenge-driven Genai4eu Booster In Apply AI Prioritised Sectors (RIA) (AI/Data/Robotics Partnership)
HORIZON Research and Innovation Actions
Basic Information
- Identifier
- HORIZON-CL4-2026-04-DIGITAL-EMERGING-19
- Programme
- DIGITAL
- Programme Period
- 2021 - 2027
- Status
- Open (31094502)
- Opening Date
- January 15, 2026
- Deadline
- April 15, 2026
- Deadline Model
- single-stage
- Budget
- €1,000,000
- Min Grant Amount
- €1,000,000
- Max Grant Amount
- €1,000,000
- Expected Number of Grants
- 1
- Keywords
- HORIZON-CL4-2026-04-DIGITAL-EMERGING-19HORIZON-CL4-2026-04Aeronautical Design and Systems IntegrationArtificial intelligence, intelligent systems, multi agent systemsPharmacodynamicsThe manufacturing aeronautics industry
Description
Project results are expected to contribute to all of the following expected outcomes:
- Significant technology progress and innovation through challenge-driven approach in the fields of aerospace, pharma/drug development or telecommunication networks.
- Increased competitivity and visibility of the Generative AI community in Europe, in demonstrating their capability to achieve challenging tasks within the aerospace, pharma/drug development or telecommunication sectors.
- Increased adoption of Generative AI in aerospace, pharma/drug development or telecommunication networks through tangible progress and achievement demonstrated via the challenge-driven process.
Generative AI (GenAI) promises to transform most industry sectors. This challenge-driven initiative aims to boost both Europe’s developer community and the adoption of powerful trustworthy generative AI solutions in the strategic sectors of aerospace, pharma/drugs and telecommunication networks, key for their competitiveness. In pharmaceuticals, it can, for instance, accelerates drug design by rapidly creating target-specific molecules, reducing development time from years to seconds, and potentially preventing prolonged health crises like COVID-19. In aerospace, generative AI can for instance optimize aircraft design, streamline manufacturing processes, predict maintenance needs through sensor data analysis, route optimisation, and enhance pilot training with diverse, realistic simulations. By embracing generative AI, telecom companies can position themselves at the forefront of a new era of intelligent and automated telecommunications. Specific use-cases include for instance network management, network optimization, network slicing, network healing, predictive maintenance, network mapping and optimization.
Each proposal should focus exclusively on one of the three key sectors mentioned above: aerospace, pharma/drug development, or telecommunications and clearly specify which sector it addresses. Each proposal is expected to focus primarily on the definition, the organization of a multi-stage competition in the chosen sector, as well as the accompanying support to the companies/teams taking part in the challenges, and related activities to maximise the impact of the action.
User industry companies from the strategic sector targeted by the proposal should be core partners in the consortium. They should demonstrate a genuine interest in the projects results and therefore support the challenge participants - in order to reach the most powerful and exploitable results benefitting their industry. The expected results are pre-competitive but the proposal must include a draft exploitation plan outlining commitments on future exploitation. The consortium is responsible for the various stages of the challenges and should provide the necessary support resources during each stage of the competition, including technical assistance and business support to develop an exploitation strategy, but most importantly, provide to the competing FSTP recipients the data necessary to fine-tune models and build powerful solutions meeting industry needs.
Proposals should be driven by impactful use-cases where generative AI can make the difference: a number of industries from the targeted sector are expected to join forces to define challenging problems to solve with GenAI solutions, which then drive the rest of the project. Based on such challenges, the consortium organises a multi-staged competition with an increasing level of complexity. In the different stages (see below), third parties, either single SMEs or small team of organisations led by an SME, compete to address the challenges with GenAI solutions.
For each proposal:
- Stage 1 - Open call: The consortium launches an open call for proposals. A challenge, open to all, will allow to select for Stage 2 the 20 highest-ranked proposals, according to a pre-defined selection process and criteria. Each solution competing for the challenge can be submitted either by a single SME, developer of GenAI solutions, or a small team of organisations led by such SME
- Stage 2 - Competition among Stage 1 winners: The 20 teams or organisations selected from Stage 1 receive EUR 250 000 FSTP grant each in accordance with their successfully selected proposal (which addresses the tasks and challenges defined for this stage by the consortium). At the end of Stage 2, the 4 highest ranked solutions will be selected for the next stage according to a pre-defined selection process and criteria.
- Stage 3– Grand finale (Competition among Stage 2 winners): The 4 teams or organisations selected from Stage 2 receive EUR 2,000,000 FSTP grants each in accordance with their successfully selected proposals to address the tasks and challenges for this stage. In conjunction, they will prepare for the grand finale that will identify the best performing solution at the end of Stage 3 according to the evaluation methodology defined by the consortium.
The consortium should define measures to support the winners in maximizing the impact and uptake of their solutions. For instance, after the end of the FSTP grant, the best performing team could be offered the opportunity to conclude partnerships or contracts with the user industries leading the consortium. Measures to support the broad uptake of their solutions in the whole sector should also be considered.
Such multi-staged scheme is expected to be implemented in parallel by the projects funded under this action, each addressing a different sector.
Each proposal, involving several major industry players, should define a clear methodology to implement the various steps of the approach, define the specifications of the stages of the competitions, timelines, targets, KPIs, a solid evaluation methodology including evaluation criteria. The main information should be in the proposal, in addition to all mandatory requirements as concerns financial support to third parties. The beneficiaries will also be in charge of implementing the evaluation methodology, and providing the necessary infrastructure/technical support for the participants to the challenges. The consortium members are also responsible for ensuring high visibility of the competitions.
The projects selected from this call, each addressing one of the three targeted sectors, are expected to collaborate among themselves, in order to make economies of scale in sharing best practices, defining processes for organising the challenges, ensuring efficient monitoring, organising dissemination and communication activities, etc. Such collaboration among the linked actions is expected to be formalised by a collaboration agreement, after the grant agreement signature.
For each proposal, an amount of EUR 5,000,000 is foreseen to be distributed among the winners of Stage 1, in form of FSTP grants, in order to prepare for Stage 2. In addition, a budget of EUR 8,000,000 is foreseen to be distributed among the winners of Stage 2, in the form of FSTP grants, to prepare for Stage 3 of the challenge.
The proposal is expected to make the case for such investment in defining the objectives with sufficient level of information. This amount will be distributed equally among the 4 winning teams of Stage 2, who are expected to develop further their solutions and compete for Stage 3.
Visibility would be important; therefore dissemination and communication campaigns are key. The proposers are also encouraged to seek sponsorship, which would be key for the visibility and prestige of their challenge, and to attract the best developers from the eligible countries to compete, particularly SMEs, alone or within a team competing for the challenges.
All proposals are expected to incorporate mechanisms for assessing and demonstrating progress, including qualitative and quantitative KPIs, benchmarking, and progress monitoring.
When possible, proposals should build on and reuse public results from relevant previous funded actions. Communicable results should be shared with the European R&D community through the AI-on-demand platform, and if necessary, other relevant digital resource platforms to bolster the European AI, Data, and Robotics ecosystem by disseminating results and best practices.
This topic implements the co-programmed European Partnership on AI, data and robotics (ADRA), and all proposals are expected to allocate tasks for cohesion activities with ADRA and the CSA HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub.
Proposals should also build on or seek collaboration with relevant projects[1] and develop synergies with other relevant International, European, national or regional initiatives. Projects selected in this topic will link to the resources offered by the AI Factories, including the Data Labs. The results may be validated in the Testing and Experiment Facilities and further deployed via the European Digital Innovation Hubs (EDIHs) and will contribute to the Apply AI strategy[2].
[1] In particular, proposals in telecommunication should exploit potential synergies with projects funded under HORIZON-CL4-2025-03-DATA-08, HORIZON-CL4-2025-03-DATA-09 and HORIZON-CL4-2025-04-DATA-02; proposals in pharma/drug should exploit potential synergies with relevant projects from Cluster 1 and IHI Innovative Health Initiative; proposals in the aerospace should exploit potential synergies with relevant projects from the clean aviation JU and other similar projects/initiatives.
[2] COM(2025) 723 Apply AI Strategy.
Destination & Scope
Leadership in frontier technologies such as Artificial Intelligence, Quantum, Photonics and Semiconductors is essential to Europe’s economic security and global competitiveness. Building on the ambition of becoming the “AI Continent” and in line with the concrete actions devised in the Apply AI Strategy[1], the EU will consolidate its world-class research ecosystem through initiatives like the RAISE network of AI science labs, the development of safe and efficient frontier AI models, and the deployment of next-generation AI agents and robotics in strategic sectors. In parallel, a long-term quantum strategy will reinforce Europe’s excellence across quantum computing, sensing and communication, supported by new infrastructures and standardisation to secure technological sovereignty. Photonics and semiconductor technologies will remain critical enablers for the digital and green transitions, with investments in advanced integrated photonic devices and resilient semiconductor ecosystems ensuring Europe’s capacity to innovate, scale and compete globally. Foresight and support to emerging materials and technologies will further strengthen Europe’s position at the cutting edge to make sure Europe’s does not miss the emergence of new disruptive technologies, aligning with the Draghi report and the Competitiveness Compass to secure a cohesive, sovereign and future-proof European industrial base.
Legal entities established in China are not eligible to participate in both Research and Innovation Actions (RIAs) and Innovation Actions (IAs) falling under this destination. For additional information please see “Restrictions on the participation of legal entities established in China” found in General Annex B of the General Annexes.
[1] COM(2025)723 Apply AI Strategy
Eligibility & Conditions
General conditions
1. Admissibility Conditions: Proposal page limit and layout
2. Eligible Countries
Described in Annex B of the Work Programme General Annexes.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide.
3. Other Eligible Conditions
In order to achieve the expected outcomes, and safeguard the Union’s strategic assets, interests, autonomy, and security, it is important to avoid a situation of technological dependency on a non-EU source, in a global context that requires the EU to take action to build on its strengths, and to carefully assess and address any strategic weaknesses, vulnerabilities and high-risk dependencies which put at risk the attainment of its ambitions. For this reason, participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, Republic of Korea, New Zealand, Switzerland, and the United Kingdom. In addition, entities established in third countries which may become associated to Horizon Europe during 2026 and 2027 may be eligible to participate in this topic if the third country is identified for this topic as an eligible country in the List of Participating Countries in Horizon Europe at the time of submission of the application[[See the List of Participating Countries in Horizon Europe available at https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/common/guidance/list-3rd-country-participation_horizon-euratom_en.pdf.]]. In any case, the association agreement to the Programme must apply by the time of the signature of the grant agreement.
For the duly justified and exceptional reasons listed in the paragraph above, in order to guarantee the protection of the strategic interests of the Union and its Member States, entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees.[[ The guarantees shall in particular substantiate that, for the purpose of the action, measures are in place to ensure that: a) control over the applicant legal entity is not exercised in a manner that retrains or restricts its ability to carry out the action and to deliver results, that imposes restrictions concerning its infrastructure, facilities, assets, resources, intellectual property or know-how needed for the purpose of the action, or that undermines its capabilities and standards necessary to carry out the action; b) access by a non-eligible country or by a non-eligible country entity to sensitive information relating to the action is prevented; and the employees or other persons involved in the action have a national security clearance issued by an eligible country, where appropriate; c) ownership of the intellectual property arising from, and the results of, the action remain within the recipient during and after completion of the action, are not subject to control or restrictions by non-eligible countries or non-eligible country entity, and are not exported outside the eligible countries, nor is access to them from outside the eligible countries granted, without the approval of the eligible country in which the legal entity is established.]]
described in Annex B of the Work Programme General Annexes.
4. Financial and operational capacity and exclusion
Described in Annex C of the Work Programme General Annexes.
5a. Evaluation and award: Award criteria, scoring and thresholds
To ensure a balanced portfolio covering the different strategic sectors, grants will be awarded to applications not only in order of ranking but at least also to one proposal that is the highest ranked within (i) the aerospace sector, (ii) the pharma/drug development sector, and (iii) the telecommunication sector, provided that the applications attain all thresholds.
Are described in Annex D of the Work Programme General Annexes.
5b. Evaluation and award: Submission and evaluation processes
are described in Annex F of the Work Programme General Annexes and the Online Manual.
5c. Evaluation and award: Indicative timeline for evaluation and grant agreement
Described in Annex F of the Work Programme General Annexes.
6. Legal and financial set-up of the grants
Beneficiaries must provide financial support to third parties. The support to third parties can only be provided in the form of grants. FSTP grants may be provided to either a single SME or to a small team of legal entities. Where provided to a small team, the coordinator (lead applicant) must be an SME and other recipients of financial support must be either an SME, a research organisation, and/or public body secondary or higher education establishment.
FSTP amounts:
- The maximum amount to be granted per FSTP grant (whether provided to one legal entity or a team of legal entities) is EUR 250,000 in stage 2 and EUR 2,000,000 in stage 3.
- The amount of EUR 250,000 in stage 2 is justified as the challenge and corresponding tasks defined for this stage must be complex enough in order to take the best and most informed decision in the selection for the next stage based on a convincing technical prototype/proof of concept that reaches sufficient level of performance in terms of scale and maturity.
- The amount of EUR 2,000,000 in stage 3 is justified by the ambition of reaching significant technology progress and innovation, defined in the expected outcome of the call, including the need for the selected projects to scale their solutions to the maturity expected.
The maximum amount to be granted to each third party is EUR 2,250,000
In accordance with Annex 5 of the grant agreement “SPECIFIC RULES FOR CARRYING OUT THE ACTION (— ARTICLE 18) Implementation in case of restrictions due to strategic assets, interests, autonomy or security of the EU and its Member States”, by default beneficiaries must ensure that, inter alia, no recipient of FSTP is (i) established in a country which is not an eligible country (as identified in the specific conditions for eligibility) or (ii) controlled by such countries or entities from such countries (directly or indirectly as per the specific conditions for eligibility). In line with the possibility for the granting authority to agree otherwise, as concerns control of SMEs or private research organisations that participate as recipients of FSTP, beneficiaries must only ensure that such entities are not directly majority-owned (i.e., more than 50% of the capital) by entities established in non-eligible countries.
Described in Annex G of the Work Programme General Annexes.
Specific conditions
described in the [specific topic of the Work Programme]
Application and evaluation forms and model grant agreement (MGA):
Application form templates — the application form specific to this call is available in the Submission System
Standard application form (HE RIA, IA)
Evaluation form templates — will be used with the necessary adaptations
Standard evaluation form (HE RIA, IA)
Guidance
Model Grant Agreements (MGA)
Call-specific instructions
Information on financial support to third parties (HE)
Ownership Control Declaration Annex (new template to be added in January 2026)
Additional documents:
HE Main Work Programme 2026-2027 – 1. General Introduction
HE Main Work Programme 2026-2027 – 7. Digital, Industry and Space
HE Main Work Programme 2026-2027 – 15. General Annexes
HE Framework Programme 2021/695
HE Specific Programme Decision 2021/764
EU Financial Regulation 2024/2509
Rules for Legal Entity Validation, LEAR Appointment and Financial Capacity Assessment
EU Grants AGA — Annotated Model Grant Agreement
Funding & Tenders Portal Online Manual
Frequently Asked Questions About Challenge-driven Genai4eu Booster In Apply AI Prioritised Sectors (RIA) (AI/Data/Robotics Partnership)
Support & Resources
Online Manual is your guide on the procedures from proposal submission to managing your grant.
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